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Oncogenesis- kaleidoscopic and multi-level reality [PDF]
Journal of Mind and Medical Sciences, 2019 Oncogenesis is an extremely complex phenomenon. The mechanisms by which cancer is induced is only partially known. Consequently, therapeutic targets may be uncertain and results are often unsatisfactory.
Firmilian Calotă +3 more
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Viruses, 2022 Marek’s disease virus (MDV) is a member of alphaherpesviruses associated with Marek’s disease, a highly contagious neoplastic disease in chickens. The availability of the complete sequence of the viral genome allowed for the identification of major genes
Weicheng Li +4 more
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Microorganisms, 2021 Marek’s disease (MD) is an immunosuppressive and highly contagious lymphoproliferative disease caused by Marek’s disease virus (MDV) in poultry. Lymphoblastoid cell lines (LCLs) generated ex vivo from MD lymphomas are considered excellent models to study
Poornima Roy +3 more
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Therapeutic approaches targeting CD95L/CD95 signaling in cancer and autoimmune diseases
Cell Death and Disease, 2022 Cell death plays a pivotal role in the maintenance of tissue homeostasis. Key players in the controlled induction of cell death are the Death Receptors (DR).
Vesna Risso +2 more
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SARS-CoV-2 integral membrane proteins shape the serological responses of patients with COVID-19
iScience, 2021 Summary: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic has elicited a unique mobilization of the scientific community to develop efficient tools to understand and combat the infection.
Sophie Martin +8 more
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Scientific Reports, 2023 Circulating tumor cells (CTC) have been studied in various solid tumors but clinical utility of CTC in small cell lung cancer (SCLC) remains unclear. The aim of the CTC-CPC study was to develop an EpCAM-independent CTC isolation method allowing isolation
Charles Ricordel +17 more
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OncoImmunology, 2022 Myeloid-derived suppressor cells (MDSCs) have been demonstrated to suppress antitumor immunity and induce resistance to PD-1/PD-L1 blockade immunotherapy in gastric and colon cancer patients.
Yao Tang +8 more
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Effectiveness of EGFR/HER2-targeted drugs is influenced by the downstream interaction shifts of PTPIP51 in HER2-amplified breast cancer cells [PDF]
, 2013 Breast cancer is the most common female cancerous disease and the second most cause of cancer death in women. About 20-30% of these tumors exhibit an amplification of the HER2/ErbB2 receptor, which is coupled to a more aggressive and invasive growth of ...
Brobeil, Alexander +4 more
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EIF3i Promotes Colon Oncogenesis by Regulating COX-2 Protein Synthesis and β-Catenin Activation [PDF]
, 2014 Translational control of gene expression has recently been recognized as an important mechanism controlling cell proliferation and oncogenesis and it mainly occurs in the initiation step of protein synthesis that involves multiple eukaryotic initiation ...
Dong, Zizheng +3 more
core +7 more sources
The von Willebrand factor stamps plasmatic extracellular vesicles from glioblastoma patients
Scientific Reports, 2021 Glioblastoma is a devastating tumor of the central nervous system characterized by a poor survival and an extremely dark prognosis, making its diagnosis, treatment and monitoring highly challenging.
Quentin Sabbagh +8 more
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