Results 21 to 30 of about 80,296 (266)
MethodsX, 2018 Zebrafish (Danio rerio) has emerged as a powerful animal model to study developmental processes and human diseases. The introduction of CRISPR/Cas9 as a genome editing tool allowed the generation of genetic mutants with high-throughput (Varshney et al ...
Erica Bresciani +2 more
doaj +1 more source
STAR Protocols, 2022 Summary: This protocol describes a flow cytometry approach to evaluate antibody responses against SARS-CoV-2 transmembrane proteins in COVID-19-positive patient sera samples without the need of specific laboratory facilities for viral infection.
Sophie Martin +6 more
doaj +1 more source
Role of Bacteria in Oncogenesis [PDF]
Clinical Microbiology Reviews, 2010 SUMMARYAlthough scientific knowledge in viral oncology has exploded in the 20th century, the role of bacteria as mediators of oncogenesis has been less well elucidated. Understanding bacterial carcinogenesis has become increasingly important as a possible means of cancer prevention.
Alicia H, Chang, Julie, Parsonnet
openaire +2 more sources
Gut microbiota–derived short‐chain fatty acids regulate group 3 innate lymphoid cells in HCC
Hepatology, EarlyView., 2022 Abstract Background and Aims Type 3 innate lymphoid cells (ILC3s) are essential for host defense against infection and tissue homeostasis. However, their role in the development of HCC has not been adequately confirmed. In this study, we investigated the immunomodulatory role of short‐chain fatty acids (SCFAs) derived from intestinal microbiota in ILC3
Chupeng Hu +11 more
wiley +1 more source
Dual IRE1 RNase functions dictate glioblastoma development
EMBO Molecular Medicine, 2018 Proteostasis imbalance is emerging as a major hallmark of cancer, driving tumor aggressiveness. Evidence suggests that the endoplasmic reticulum (ER), a major site for protein folding and quality control, plays a critical role in cancer development. This
Stéphanie Lhomond +27 more
doaj +1 more source
JHEP Reports, 2023 Background & Aims: Intrahepatic cholangiocarcinoma (iCCA) is a deadly cancer worldwide with an increasing incidence and limited therapeutic options.
Corentin Louis +11 more
doaj +1 more source
The Regulation of Telomerase in Oncogenesis
Acta Naturae, 2009 The influence that the expression of the human (glial-derived neurotrophic factor (GDNF)) neurotrophic factor has on the morphology and proliferative activity of embryonic stem cells (SC) of a mouse with R1 lineage, as well as their ability to form embroid bodies (EB), has been studied.
Skvortzov, D. +4 more
openaire +3 more sources
Reliable blood cancer cells' telomere length evaluation by qPCR
Cancer Medicine, 2020 Background Telomere shortening is linked to a range of different human diseases, hence reliable measurement methods are needed to uncover such associations.
Joana Ropio +10 more
doaj +1 more source
Oropharyngeal Shedding of Gammaherpesvirus DNA by Cats, and Natural Infection of Salivary Epithelium
Viruses, 2022 Felis catus gammaherpesvirus-1 (FcaGHV1), a novel candidate oncogenic virus, infects cats worldwide. Whether the oropharynx is a site of virus shedding and persistence, and whether oronasal carcinomas harbor FcaGHV1 nucleic acid were investigated.
Elizabeth C. Rose +9 more
doaj +1 more source
Nature Communications, 2016 Translesion synthesis polymerase eta has a well characterized role in replicating past UV-induced DNA lesions and has recently been shown to act at difficult to replicate sequences.
Emmanuelle Despras +5 more
doaj +1 more source