Results 171 to 180 of about 80,296 (266)

Altered Nasal Microbiota in Sinonasal Tumors: A Comparative Analysis of Malignant and Benign Sinonasal Tumors

open access: yesInternational Forum of Allergy &Rhinology, Volume 16, Issue 8, Page 778-787, August 2026.
ABSTRACT Background Although shifts in nasal microbiota have been well‐documented in inflammatory upper airway conditions, microbiota tumor‐associated alterations remain uncharacterized. This study is the first to compare sinonasal microbiota profiles of patients with malignant tumors (MT), benign tumors (BT), and controls, offering insights into tumor‐
Evan A. Patel   +13 more
wiley   +1 more source

The physiology of survival: Space

open access: yes
Experimental Physiology, EarlyView.
Damian M. Bailey, Angelique van Ombergen
wiley   +1 more source

Targeting Human Protein Kinase CK2 by a Library of Indeno[1,2‐b]Indoles: Contribution of Thermal Shift Assay to Pre‐Screening and Co‐Crystallization to Post‐Screening

open access: yesArchiv der Pharmazie, Volume 359, Issue 8, August 2026.
A series of 25 functionalized indeno[1,2‐b]indoles was selected from in‐house compound library and additional synthesis work. Capillary electrophoresis‐based and thermal shift assays, X‐ray analysis of small molecules, and co‐crystallization studies highlighted a key molecular template for the inhibitory potential of protein kinase CK2.
Matheus M. Guimarães   +18 more
wiley   +1 more source

Novel Disease-Specific Panel of Salivary microRNAs for the Detection of Oral Squamous Cell Carcinoma from Early Invasion to Stage IV Disease. [PDF]

open access: yesInt J Mol Sci
Gintoni I   +8 more
europepmc   +1 more source

Preoperative Avapritinib for Localized PDGFRA‐Mutant GIST: Marked Pathologic Response, but Limited Feasibility at Standard Dosing

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
In this two‐center retrospective series of eight patients with localized PDGFRA‐mutant gastric GIST treated with preoperative avapritinib, therapy produced substantial antitumor activity, including tumor reduction in 7 of 8 patients and complete or near‐complete pathologic response in all resected patients.
Tannaz Ranjbarian   +8 more
wiley   +1 more source

Patient‐Derived Organoid‐Based CRISPR Screens in Cancer Research: Applications, Advances, and Challenges

open access: yesCancer Medicine, Volume 15, Issue 8, August 2026.
ABSTRACT Patient‐derived organoids (PDOs) have emerged as physiologically relevant cancer models that preserve key genetic, histological, and functional features of the tumors from which they are derived. In parallel, CRISPR‐based perturbation technologies have transformed functional genomics by enabling scalable interrogation of gene function.
Julianne du Plessis, Aadilah Omar
wiley   +1 more source

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