Results 181 to 190 of about 80,296 (266)

Phytochemical Profiling and Biological Evaluation of Anthyllis henoniana Organs: Integrated In Vitro and Molecular Docking Insights Into Antioxidant, Anti‐Inflammatory, and Cytotoxic Potential

open access: yesChemistry &Biodiversity, Volume 23, Issue 8, August 2026.
Anthyllis henoniana aerial parts were subjected to fractionated extraction. Methanolic fractions yielded high total phenolic and flavonoid contents with strong antiradical (anti‐DPPH) and neuroprotective (anti‐AChE) activities, whereas dichloromethane and cyclohexane fractions demonstrated potent cytotoxicity (anti‐MCF‐7, anti‐HCT‐116) and anti ...
Sabrine Jaber   +3 more
wiley   +1 more source

Activation of a TFAM‐Dependent Mitochondrial Translational Axis Drives Oxidative Metabolism in Grade 2 Meningiomas

open access: yesCell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT Meningiomas exhibit marked biological heterogeneity that is not fully captured by current histopathological grading. Increasing evidence suggests that mitochondrial metabolism contributes to tumor aggressiveness; however, the molecular mechanisms regulating mitochondrial function in meningiomas remain poorly defined.
Stella G. Cavalcante   +5 more
wiley   +1 more source

Dietary Terpenoids in Advancing Biofilm‐Mediated Cancer Prevention: Antibiofilm Cascade, Molecular Crosstalk, and Nano‐Facilitated Functional Delivery

open access: yesCell Biochemistry and Function, Volume 44, Issue 8, August 2026.
ABSTRACT The role of microbes in cancer is gaining attention these days, especially in the context of tumor‐associated biofilms and dysbiotic microbiota. Biofilm‐producing microorganisms, such as Fusobacterium nucleatum and Helicobacter pylori, trigger oncogenic inflammation and immune evasion in tumor initiation and progression, and in the development
Saikat Mazumder   +14 more
wiley   +1 more source

C1s protects cutaneous squamous carcinoma cells from TRAIL-induced apoptosis. [PDF]

open access: yesOncogenesis
Salmela M   +7 more
europepmc   +1 more source

Integrated Network Analysis Suggests an miR‐21/MMP/VEGF‐Associated Regulatory Axis in Gastric Cancer

open access: yesCancer Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background, Aims Gastric cancer (GC) pathogenesis involves complex molecular interactions that remain incompletely understood at a biological systems level. While microRNA‐21 (miR‐21), matrix metalloproteinases (MMPs), and vascular endothelial growth factor (VEGF) have been individually implicated in GC, their integrated role as a coordinated ...
Fatemeh Babajani, Hadi Mozafari
wiley   +1 more source

Germline Pathogenic Variants in Homologous Recombination Pathway Genes Are Frequent in Pancreatobiliary Ampullary Carcinoma. [PDF]

open access: yesJCO Precis Oncol
Misyura M   +10 more
europepmc   +1 more source

Neuroprotective Role of E3 Ubiquitin Ligase TRIM2 in Parkinson's Disease: Attenuation of Oxidative Stress and Apoptosis via Promoting ELAVL1 Ubiquitination

open access: yesCNS Neuroscience &Therapeutics, Volume 32, Issue 8, August 2026.
The E3 ubiquitin ligase TRIM2 confers neuroprotection against 6‐OHDA‐induced oxidative stress and apoptosis. It exerts this function by binding to ELAVL1 and promoting its degradation via the ubiquitin‐proteasome pathway. Thus, our study reveals the TRIM2‐ELAVL1 axis as a key regulatory mechanism for neuronal survival under 6‐OHDA‐stimulated toxic ...
Wei Liang   +4 more
wiley   +1 more source

On the potential origin of the zygote-like cancer stem cell with a focus on fusion for cell rescue. [PDF]

open access: yesFront Cell Dev Biol
Cismaru CA   +4 more
europepmc   +1 more source

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