Results 191 to 200 of about 137,458 (285)

The ZNF148‐ZEB1‐AS1‐IGF2BP2‐NOD2 Axis Drives Microglial Antipneumococcal Immunity in Bacterial Meningitis

Glia, Volume 74, Issue 2, February 2026.
ZNF148 upregulates ZEB1‐AS1, which scaffolds IGF2BP2 to stabilize NOD2 mRNA, enhancing microglial anti‐pneumococcal immunity via cytokine production and bacterial clearance in bacterial meningitis. ABSTRACT Streptococcus pneumoniae (Spn) meningitis remains a lethal central nervous system (CNS) infection with limited therapies. This study identifies the
Xiufu Hu, Fang Jiang, Xinjie Liu, Ling Li, Ruimei Hu, Meng Dong, Aihua Cao   +6 more
wiley   +1 more source

Oncovirus classification and insights into herpes simplex virus, Varicella-Zoster virus. [PDF]

Cancer Cell Int
Ghaemi A, Sadeh S.
europepmc   +1 more source

Genetic variants underlying precancerous conditions of hepatocellular carcinoma

International Journal of Cancer, Volume 158, Issue 3, Page 488-502, 1 February 2026.
Abstract Hepatocellular carcinoma (HCC) is the most common form of liver cancer, accounting for 80% of cases worldwide. While chronic hepatitis B and C infections remain primary risk factors, emerging evidence highlights the increasing contributions of metabolic dysfunction‐associated steatotic liver disease (MASLD) and alcohol‐associated liver disease
Jonathan Jaime G. Guerrero, Paolo C. Encarnacion, Mark Angelo S. del Rosario, Matthew Aldren S. Ora, Jiayan Zhou, Kin Israel Notarte, Wan‐Chun Li, Ching‐Wen Chang   +7 more
wiley   +1 more source

Correction: eIF4E S209 phosphorylation licenses myc- and stress-driven oncogenesis.

Elife
Ruan H, Li X, Xu X, Leibowitz BJ, Tong J, Chen L, Ao L, Xing W, Luo J, Yu Y, Schoen RE, Sonenberg N, Lu X, Zhang L, Yu J.   +14 more
europepmc   +1 more source

Unlocking the tumor microenvironment: Innovative strategies for cancer therapy and translational insights. [PDF]

Cell Rep Med
Panada E, Kuznetsova T, Hamilton S.
europepmc   +1 more source

New cell lines expanding the diversity of Ewing sarcoma models

International Journal of Cancer, Volume 158, Issue 3, Page 642-655, 1 February 2026.
What's new? A chromosomal translocation between the EWSR1 and ETS genes is the key oncogenic driver in Ewing sarcoma. EWSR1::FLI1, the most frequent fusion, is subdivided into different fusion types with unclear prognostic relevance. Here, the authors describe the establishment and characterization of four new, intrinsically immortal, patient‐derived ...
Maximilian Kerkhoff, Christiane Schaefer, Wilhelm G. Dirks, Dawid Krzeciesa, Maximilian Bretschneider, Pauline R. Plaumann, Wiebke K. Guder, Arne Streitbürger, Sonja Herter, Heike Peterziel, Ina Oehme, Felina Zahnow, Thomas G. P. Grünewald, Uta Dirksen   +13 more
wiley   +1 more source

Enhanced Expression of IL32 mRNA in Skeletal Muscles in the Context of Head and Neck Carcinomas

Journal of Cachexia, Sarcopenia and Muscle, Volume 17, Issue 1, February 2026.
ABSTRACT Background Cancer‐related sarcopenia (CRS) is a significant complication of head and neck carcinoma (HNC), characterised by muscle degeneration and poor clinical outcomes. Although various dietary and therapeutic interventions have been explored, most of them remain empirical, and the molecular mechanisms underlying CRS are not yet fully ...
Imane Baïche, Héla Hachicha, Thierry Ragot, Céline Gracia, Aurore Gelin, Anaïs Gader, Caroline Even, Ingrid Breuskin, Odile Casiraghi, Thibault Dayris, Filippo Dall'Ollio, Catherine Brenner, Karim Benihoud, Yegor Vassetzky, François Bidault, Philippe Gorphe, Pierre Busson, Fei Chen   +17 more
wiley   +1 more source

Editorial: Synthetic biology and metabolomics: novel insight in oncology research. [PDF]

Front Bioeng Biotechnol
Dhar R, Pethusamy K, Paul MK, Karmakar S.   +3 more
europepmc   +1 more source

Inhibition of FOS‐Like Antigen 1 Reduces Chemoresistance to Temozolomide Through Stemness Reprogramming via IL‐6/STAT3Tyr705 Pathway

MedComm, Volume 7, Issue 2, February 2026.
The role of FOSL1 in TMZ response to GBM. FOSL1 enhances TMZ resistance by promoting cell cycle progression, MGMT expression, and IL‐6‐pSTAT3Tyr705‐stemness axis. VEM is a potential candidate drug for alleviating TMZ resistance in GBM, highlighting a new approach for chemo‐resistant GBM treatment.
JeongMin Sim, JeongMan Park, JinHyung Heo, Yu Jin Kim, Dongkil Kim, Yong Hyun Jeon, Jae‐Eon Lee, Seon Hee Choi, Hak Jin Kim, So Jung Hwang, Junhyung Kim, Kyung Gi Cho, Jihwan Yoo, Ju Hyung Moon, Jong‐Seok Moon, Kyoung Su Sung, Jaejoon Lim   +16 more
wiley   +1 more source

The Complexity of Bovine Leukemia Virus Oncogenesis. [PDF]

Viruses
Doucet F, Fontaine A, Hamaidia M, Jacques JR, Jouant T, Mhaidly N, Qin S, Terres R, Saintmard X, Willems L, Zwaenepoel M.   +10 more
europepmc   +1 more source