Results 211 to 220 of about 137,458 (285)

Correction: Use of constitutive and inducible oncogene-containing iPSCs as surrogates for transgenic mice to study breast oncogenesis. [PDF]

Stem Cell Res Ther
Nguyen C, Nguyen JPT, Modi AP, Ahmad I, Petrova SC, Ferrell SDJ, Wilhelm SR, Ye Y, Schaue D, Barsky SH.   +9 more
europepmc   +1 more source

Mechanisms of enhancer‐driven oncogene activation

International Journal of Cancer, Volume 158, Issue 2, Page 333-341, 15 January 2026.
Abstract An aggressive subtype of acute myeloid leukemia (AML) is caused by enhancer hijacking resulting in MECOM overexpression. Several chromosomal rearrangements can lead to this: the most common (inv(3)/t(3;3)) results in a hijacked GATA2 enhancer, and there are several atypical MECOM rearrangements involving enhancers from other hematopoietic ...
Joyce Vriend, Ruud Delwel, Dorien Pastoors   +2 more
wiley   +1 more source

Roles of Macrophage Migration Inhibitory Factor (MIF) Signaling Pathway in Oncovirus Infection and Virus-Associated Cancers. [PDF]

Viruses
Fan J, Ryu V, Qin Z, Dai L.
europepmc   +1 more source

Differential module analysis in neuroblastoma regulatory networks [PDF]

, 2014
Beckers, Anneleen, Cannoodt, Robrecht, De Preter, Katleen, Saeys, Yvan, Van Cauwenbergh, Caroline   +4 more
core   +1 more source

Therapeutic targeting of chromatin alterations in leukemia and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 382-408, 15 January 2026.
Abstract Alterations in chromatin conformation and post‐translational modification of histones have become increasingly recognized as critical drivers of cancer development, progression, and therapy resistance. Recent advances in drug development have led to the establishment of several highly selective small molecule inhibitors, several of which are ...
Florian Perner, Tobias Berg, Daniel Sasca, Sophie‐Luise Mersiowsky, Jayant Y. Gadrey, Johanna Thomas, Michael W. M. Kühn, Michael Lübbert   +7 more
wiley   +1 more source

HIV-associated gut dysbiosis drives oncogenesis through metabolic-immune crosstalk: mechanisms and therapeutic implications. [PDF]

Front Oncol
Meng Q, Xu L, Xu F, Shen X, Yue J.
europepmc   +1 more source

DNA methyltransferase inhibitors in hematological malignancies and solid tumors

International Journal of Cancer, Volume 158, Issue 2, Page 433-461, 15 January 2026.
Abstract Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...
Valentin Wenger, Guillermo Garcia‐Manero, Robert Zeiser, Michael Lübbert   +3 more
wiley   +1 more source

COVID-19 and Lung Cancer Interactions: A Literature Review. [PDF]

Med Sci (Basel)
László SA, Ianoși ES, Văsieșiu AM, Szathmáry M, Ianoși MB, Rachiș DL, Nistor G, Jimborean G.   +7 more
europepmc   +1 more source

LncRNA DANCR Activates p38/mTOR‐Mediated Autophagy via ANXA2 to Exacerbate Oxygen‐Induced Retinal Neovascularization in Mice

The FASEB Journal, Volume 40, Issue 1, 15 January 2026.
This study reveals that the long non‐coding RNA DANCR drives pathological retinal neovascularization in oxygen‐induced retinopathy via an ANXA2‐dependent p38/MAPK/mTOR autophagy pathway. In hypoxic endothelial cells and a murine OIR model, DANCR promotes angiogenesis.
Yini Wang, Jiale Bai, Shihong Zhao
wiley   +1 more source

The role of pioneering transcription factors, chromatin accessibility and epigenetic reprogramming in oncogenic viruses. [PDF]

Front Microbiol
Kgatle M, Mbambara S, Khoza L, Fadebi O, Mashamba-Thompson T, Sathekge M.   +5 more
europepmc   +1 more source