Results 141 to 150 of about 28,421 (276)
PLoS Computational Biology, 2019 Oncolytic virotherapies, including the modified herpes simplex virus talimogene laherparepvec (T-VEC), have shown great promise as potent instigators of anti-tumour immune effects.
Tyler Cassidy, Morgan Craig
doaj +1 more source
Oncolytic viruses as anticancer vaccines
Frontiers in Oncology, 2014 Oncolytic virotherapy has shown impressive results in preclinical studies and first promising therapeutic outcomes in clinical trials as well. Since viruses are known for a long time as excellent vaccination agents, oncolytic viruses are now designed as ...
Norman eWoller +4 more
doaj +1 more source
Doxorubicin hydrochloride enhanced antitumour effect of CEA‐regulated oncolytic virotherapy in live cancer cells and a mouse model [PDF]
, 2020 Boduan Xiao +11 more
openalex +1 more source
Cancer Innovation, Volume 4, Issue 4, August 2025.Glioblastoma (GBM) remains a highly malignant brain tumor with limited treatment efficacy, driving the need for innovative cellular immune theranostic strategies that integrate diagnostic and therapeutic approaches. Recent advances in cellular immunotherapy for GBM include chimeric antigen receptor (CAR)‐T/NK cells, macrophage‐based therapies ...
Ying Gong +14 more
wiley +1 more source
International Journal of Hyperthermia, 2019 Objective: To validate the feasibility of molecular imaging-monitored intratumoral radiofrequency hyperthermia (RFH) enhanced direct oncolytic virotherapy for hepatocellular carcinoma (HCC).
Jingjing Song +8 more
doaj +1 more source
Micro‐ and nanomotors in biomedical applications
Responsive Materials, Volume 3, Issue 3, August 2025.Micro‐ and nanomotors (MNMs), as autonomous devices converting chemical or external energy into mechanical propulsion, have emerged as transformative drug delivery platforms in biomedicine. This review systematically outlines the design principles governing MNMs' propulsion and operation, highlights the applications of MNMs in disease treatment, and ...
Xiangyu Meng, Yuqi Tang, Quan Li
wiley +1 more source
Evidence for Oncolytic Virotherapy: Where Have We Got to and Where Are We Going?
Viruses, 2015 The last few years have seen an increased interest in immunotherapy in the treatment of malignant disease. In particular, there has been significant enthusiasm for oncolytic virotherapy, with a large amount of pre-clinical data showing promise in animal ...
Samantha Turnbull +5 more
doaj +1 more source
Retargeted adenoviruses for radiation-guided gene delivery [PDF]
, 2016 The combination of radiation with radiosensitizing gene delivery or oncolytic viruses promises to provide an advantage that could improve the therapeutic results for glioblastoma. X-rays can induce significant molecular changes in cancer cells.
A Beetz +54 more
core +2 more sources
High Cell Density Perfusion Process of Quail Cells Producing Oncolytic rVSV‐NDV
Engineering in Life Sciences, Volume 25, Issue 7, July 2025.ABSTRACT Oncolytic viruses as agents for the treatment of various types of cancer have demonstrated their potential in many clinical studies over the past decades. In particular, rVSV‐NDV (a recombinant vesicular stomatitis virus [VSV] construct with fusogenic Newcastle disease virus glycoproteins) shows promising preclinical results.
Lennart Jacobtorweihe +5 more
wiley +1 more source
Oncolytic paramyxoviruses-induced autophagy; a prudent weapon for cancer therapy
Journal of Biomedical Science, 2019 Oncolytic virotherapy has currently emerged as a promising approach upon which scientists have been able to induce tumor-specific cell death in a broad spectrum of malignancies.
Mohsen Keshavarz +3 more
doaj +1 more source