Results 121 to 130 of about 8,958 (210)
Oncolytic virotherapy: the questions and the promise
Oncolytic Virotherapy, 2013 Oncolytic virotherapy is a new strategy to reduce tumor burden through selective virus replication in rapidly proliferating cells. Oncolytic viruses are members of at least ten virus families, each with its advantages and disadvantages. Here, I briefly review the recent advances and key challenges, as exemplified by the best-studied platforms.
openaire +3 more sources
Editorial: Oncolytic virotherapy
Frontiers in Molecular Biosciences, 2023 Ahmed Majeed Al-Shammari +2 more
openaire +3 more sources
Oncolytic Replication of E1b-Deleted Adenoviruses
Viruses, 2015 Various viruses have been studied and developed for oncolytic virotherapies. In virotherapy, a relatively small amount of viruses used in an intratumoral injection preferentially replicate in and lyse cancer cells, leading to the release of amplified ...
Pei-Hsin Cheng +3 more
doaj +1 more source
Development of a WNT-selective oncolytic adenovirus for imaging the therapy of colorectal cancers.
, 2008 PhDIntroduction: The concept of oncolytic adenoviruses has been validated in preclinical studies but clinical trials have demonstrated that the virus spread remains limited and the virus fails to infect all cancer cells in a tumour.
Peerlinck, Inge D L +1 more
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The Potential of Oncolytic Virotherapy in the Treatment of Head and Neck Cancer: A Comprehensive Review. [PDF]
Int J Mol SciHead and neck cancer (HNC) represents a challenging oncological entity with significant morbidity and mortality rates. Despite advances in conventional therapies, including surgery, chemotherapy, and radiation therapy, the overall survival rates for ...
Spirito F +10 more
europepmc +2 more sources
, 2011 Replication selective oncolytic viruses (OVs) are a rapidly expanding therapeutic platform for cancer treatment. OVs are characterized by genetic alterations that ablate critical viral protein functions essential for viral replication in normal cells ...
Abagnale, Antonella
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Analisa Kestabilan Model Matematika untuk Penyembuhan Kanker Menggunakan Oncolytic Virotherapy [PDF]
, 2016 . Oncolytic virotherapy is one type of cancer treatment using oncolytic virus. In this paper, we will present a mathematical model for treatment of cancer using oncolytic virotherapy with the burst size of a virus (the number of new viruses released ...
Via Novellina, Via Novellina
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A multiscale mathematical model for oncolytic virotherapy
, 2009 One of the most promising strategies to treat cancer is attacking it with viruses. Oncolytic viruses can kill tumor cells specifically or induce anticancer immune response. A multiscale model for virotherapy of cancer is investigated through simulations.
Martins, Marcelo L. +7 more
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Table_1_Delivery and Biosafety of Oncolytic Virotherapy.pdf
, 2020 In recent years, oncolytic virotherapy has emerged as a promising anticancer therapy. Oncolytic viruses destroy cancer cells, without damaging normal tissues, through virus self-replication and antitumor immunity responses, showing great potential for ...
Duoduo Han (8717601) +4 more
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