Results 111 to 120 of about 8,958 (210)
Emerging role of Natural killer cells in oncolytic virotherapy
, 2015 Rauf Bhat, Jean Rommelaere Division of Tumor Virology, German Cancer Research Center, Heidelberg, Germany Abstract: Natural killer (NK) cells constitute a subtype of lymphocytes that initiate innate immune responses against tumors and virus-infected ...
Bhat R, Rommelaere J
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Oncolytic Virotherapy for human malignant mesothelioma: recent advances
, 2015 International audienceCancer virotherapy is an attractive alternative to conventional treatments because it offers a wide range of antitumor effects due to 1) the diversity of the oncolytic viruses that are now available and 2) their multifaceted ...
Tangy, Frédéric +5 more
core +1 more source
A Cellular Automata Model of Oncolytic Virotherapy in Pancreatic Cancer
, 2020 Oncolytic virotherapy is known as a new treatment to employ less virulent viruses to specifically target and damage cancer cells. This work presents a cellular automata model of oncolytic virotherapy with an application to pancreatic cancer.
Chen, J. (author) +6 more
core +1 more source
Oncolytic potency and reduced virus tumor-specificity in oncolytic virotherapy. A mathematical modelling approach. [PDF]
, 2017 In the present paper, we address by means of mathematical modeling the following main question: How can oncolytic virus infection of some normal cells in the vicinity of tumor cells enhance oncolytic virotherapy?
De Pillis, Lisette +7 more
core +1 more source
Journal for ImmunoTherapy of Cancer, 2018 Antiviral responses are barriers that must be overcome for efficacy of oncolytic virotherapy. In mammalian cells, antiviral responses involve the interferon pathway, a protein-signaling cascade that alerts the immune system and limits virus propagation ...
Donald Bastin +8 more
doaj +1 more source
Current perspectives of virotherapy as a cancer treatment strategy
Инфекция и иммунитетAnalysis of scientific literature presented in the main databases (PubMed, CyberLeninka, Google Scholar, Scopus) evidence that after cardiovascular diseases malignant tumors hold the second place among the most common causes of mortality in both ...
Lyubov D. Vlasova
doaj +1 more source
Molecular Therapy: Oncolytics, 2017 Oncolytic virotherapy is a treatment approach with increasing clinical relevance, as indicated by the marked survival benefit seen in animal models and its current exploration in human patients with cancer.
Julius W. Kim +9 more
doaj +1 more source
Arming vaccinia virus for pancreatic cancer oncolytic virotherapy
, 2011 PhDVaccinia virus is a 250-300nm enveloped DNA virus from the poxvirus family and is used as a vector for oncolytic viral gene therapy. No unique cell surface receptor has been identified for Vaccinia virus and the reasons for its tropism for cancer ...
Hiley, Crispin
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IgE‐Sensitized Mast Cells: A Programmable Platform for Antigen‐Triggered Oncolytic Virotherapy
MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
Lin Chen, Yu‐Xuan Jin, Jin‐Lyu Sun
wiley +1 more source
, 2008 With the aim of improving viral distribution and tumor penetration, we have engineered decorin expressing replication-incompetent (dl-LacZ-DCNG) and -competent (Ad-[DELTA]E1B-DCNG) adenoviruses.
Joo-Hang Kim +7 more
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