Results 101 to 110 of about 12,104 (196)

Gene therapy of liver cancer [PDF]

, 2006
The application of gene transfer technologies to the treatment of cancer has led to the development of new experimental approaches like gene directed enzyme/pro-drug therapy (GDEPT), inhibition of oncogenes and restoration of tumor-suppressor genes.
Hernandez-Alcoceba, R. (Rubén), Prieto, J. (Jesús), Sangro, B. (Bruno)   +2 more
core   +1 more source

Strategies in Gene Therapy for Glioblastoma [PDF]

, 2013
Glioblastoma (GBM) is the most aggressive form of brain cancer, with a dismal prognosis and extremely low percentage of survivors. Novel therapies are in dire need to improve the clinical management of these tumors and extend patient survival.
Behera, Prajna, Chiocca, E. Antonio, Kwiatkowska, Aneta, Nandhu, Mohan S., Viapiano, Mariano S.   +4 more
core   +2 more sources

Oncolytic Replication of E1b-Deleted Adenoviruses

Viruses, 2015
Various viruses have been studied and developed for oncolytic virotherapies. In virotherapy, a relatively small amount of viruses used in an intratumoral injection preferentially replicate in and lyse cancer cells, leading to the release of amplified ...
Pei-Hsin Cheng, Stephen L. Wechman, Kelly M. McMasters, Heshan Sam Zhou   +3 more
doaj   +1 more source

Cytolytic Effects of Newcastle Disease Virus Strain Af2240 on Dbtrg.05mg and U-87mg Brain Tumor Cell Lines [PDF]

, 2008
Newcastle disease virus (NDV) is a potential oncolytic agent as it can replicate up to 10,000 times better in human cancer cells than in most normal human cells. Several strains of NDV were reported to induce cytolysis to various cancerous cell lines.
Saeed, Rola Ali
core  

A Dynamical Analysis on a Tumour Virotherapy Model with Standard Incident Rate [PDF]

, 2017
This paper discusses a dynamical analysis on a model that governs the growth of tumour cell under a therapy by using oncolytic viruses, on the standard incident rate.
Ikawati, D. S. (Deasy), Kusumawinahyu, W. M. (Wuryansari), Trisilowati, T. (Trisilowati)   +2 more
core  

Oncolytic Viroradiotherapy for Neuroblastoma [PDF]

, 2014
College of Education and Human Ecology Undergraduate Research ScholarshipNeuroblastoma is the most common extra-cranial solid tumor in childhood and the leading cause of childhood cancer mortality.
Kunkler, Anne
core  

Engineered bovine herpesvirus type 4: a new tool against glioma stem-like cells? [PDF]

, 2015
Glioblastoma (GBM) is a grade IV primary brain tumor (WHO 2007). Despite last progresses in surgery, chemo- and radiotherapy, this brain tumor is still incurable and it always recurs (Stupp et al, 2009).
Moschioni, Chiara
core  

Single dose GLP toxicity and biodistribution study of a conditionally replicative adenovirus vector, CRAd-S-pk7, administered by intracerebral injection to Syrian hamsters [PDF]

, 2016

core   +1 more source

Clinical and translational progress in oncolytic virotherapy for pediatric CNS tumors. [PDF]

J Neurooncol
Elgehiny A, Fan AE, Frost M, He J, Gary SE, Osorio DS, Zaky W, Zhou L, Kang KD, Zhang Z, Fueyo J, Gomez-Manzano C, Thompson EM, Bernstock JD, Friedman GK.   +14 more
europepmc   +1 more source

The Role of Viral Dynamics and Infectivity in Models of Oncolytic Virotherapy for Tumours with Different Motility. [PDF]

Bull Math Biol
Morselli D, Frascoli F, Delitala ME.
europepmc   +1 more source