Results 151 to 160 of about 28,421 (276)
Oncolytic virotherapy: new weapon for breast cancer treatment [PDF]
, 2020 Veronica Martini +5 more
openalex +1 more source
A Novel Molecular Therapy Using Bioengineered Adenovirus for Human Gastrointestinal Cancer [PDF]
, 2011 Replication-selective tumor-specific viruses constitute a novel approach for treatment of neoplastic disease. These vectors are designed to induce virus-mediated lysis of tumor cells after selective viral propagation within the tumor. Human telomerase is
Fujiwara, Toshiyoshi
core +1 more source
Oncolytic viruses: Revolutionising the fight against tumours
Clinical and Translational Medicine, Volume 15, Issue 10, October 2025.
Zeda Zhao, Yinan Shen, Tingbo Liang
wiley +1 more source
Journal for ImmunoTherapy of Cancer, 2018 Antiviral responses are barriers that must be overcome for efficacy of oncolytic virotherapy. In mammalian cells, antiviral responses involve the interferon pathway, a protein-signaling cascade that alerts the immune system and limits virus propagation ...
Donald Bastin +8 more
doaj +1 more source
Rational engineering of microRNA-regulated viruses for cancer gene therapy [PDF]
, 2013 MicroRNAs (miRNAs) are small noncoding RNA molecules that have important regulatory roles in a wide range of biological processes. miRNAs are often expressed in a tissue- and/or differentiation state-specific patterns, and it is estimated that miRNAs can
Ylösmäki, Erkko
core
Current perspectives of virotherapy as a cancer treatment strategy
Инфекция и иммунитетAnalysis of scientific literature presented in the main databases (PubMed, CyberLeninka, Google Scholar, Scopus) evidence that after cardiovascular diseases malignant tumors hold the second place among the most common causes of mortality in both ...
Lyubov D. Vlasova
doaj +1 more source
Decreasing the Susceptibility of Malignant Cells to Infection Does Not Impact the Overall Efficacy of Myxoma Virus-Based Oncolytic Virotherapy [PDF]
, 2020 Erica Flores, Eric Bartee
openalex +1 more source
Evaluation of CD46 re-targeted adenoviral vectors for clinical ovarian cancer intraperitoneal therapy [PDF]
, 2016 Ovarian cancer accounts for >140 000 deaths globally each year. Typically, disease is asymptomatic until an advanced, incurable stage. Although response to cytotoxic chemotherapy is frequently observed, resistance to conventional platinum-based therapies
A Hemminki +40 more
core +1 more source
Molecular Therapy: Oncolytics, 2017 Oncolytic virotherapy is a treatment approach with increasing clinical relevance, as indicated by the marked survival benefit seen in animal models and its current exploration in human patients with cancer.
Julius W. Kim +9 more
doaj +1 more source
Markedly enhanced intratumoral spread and antitumor effect of oncolytic adenovirus expressing decorin [PDF]
, 2008 With the aim of improving viral distribution and tumor penetration, we have engineered decorin expressing replication-incompetent (dl-LacZ-DCNG) and -competent (Ad-[DELTA]E1B-DCNG) adenoviruses.
A-Rum Yoon +7 more
core +1 more source