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New hopes for the breast cancer treatment: perspectives on the oncolytic virus therapy. [PDF]
Chowaniec H+7 more
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Characterizing Aptamer Interaction with the Oncolytic Virus VV-GMCSF-Lact. [PDF]
Dymova MA+15 more
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Pharmaceutical Patent Analyst, 2012
Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco M. Buonaguro+3 more
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Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco M. Buonaguro+3 more
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Oncolytic Virus Therapy - Foreword
Current Cancer Drug Targets, 2007We are very pleased and proud to be able to publish this special issue of Current Cancer Drug Targets devoted to oncolytic virus therapy covering basic and clinical research on adenovirus, vaccinia virus, herpes virus, and Newcastle disease virus. In these papers, we welcome the world's top authorities in the field who have generously contributed their
Naohito Kanazumi+8 more
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Oncolytic Virus Immunotherapy for Melanoma
Current Treatment Options in Oncology, 2015Melanoma is a type of skin cancer arising from melanocytes and is increasing in incidence. Although complete surgical excision of early stage lesions may be curative, metastatic melanoma continues to be a major therapeutic challenge. Advances in understanding the molecular pathways that promote tumorigenesis and the interactions between melanoma cells ...
Howard L. Kaufman+2 more
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Lymphomas and Oncolytic Virus Therapy
Clinical Lymphoma, 2003There are several well-documented cases in medical literature of the remission of leukemias and malignant lymphomas following natural human viral infections. In the hope of being able to reproduce these spontaneous tumor regressions, investigators have studied various viruses with distinct oncolytic properties. The first attempts to treat patients with
Donald G. Morris+8 more
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Virus, Oncolytic Virus and Human Prostate Cancer
Current Cancer Drug Targets, 2017Prostate cancer (PCa), a disease, is characterized by abnormal cell growth in the prostate - a gland in the male reproductive system. Although older age and a family history of the disease have been recognized as the risk factors of PCa, the cause of this cancer remains unclear.
Liu, Guang Bin+3 more
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Oscillations in a Spatial Oncolytic Virus Model
Bulletin of Mathematical Biology, 2023AbstractVirotherapy treatment is a new and promising target therapy that selectively attacks cancer cells without harming normal cells. Mathematical models of oncolytic viruses have shown predator-prey like oscillatory patterns as result of an underlying Hopf bifurcation.
Arwa Abdulla Baabdulla, Thomas Hillen
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Dynamics of an oncolytic virus model
Nonlinear Analysis: Real World Applications, 2021Abstract An ODE model for oncolytic virus dynamics with four parameters is discussed. Although it is hard to obtain the explicit expressions of coordinates of equilibria, we find distribution of equilibria qualitatively, and obtain the exact number of equilibria and their qualitative properties.
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