Results 181 to 190 of about 1,058,979 (232)

Enhanced oral nanomedicine utilizing biomineralized oncolytic virus for synergistic gastrointestinal cancer therapy. [PDF]

Mater Today Bio
Hu Z, Sun Y, Yu S, Zheng F, Yan Z, Lu N, Ye L, Yuan S, Zhu Y, Deng J, Wang J, Bai Y.   +11 more
europepmc   +1 more source

Phase 1 open-label study of ASP9801, an oncolytic virus, in patients with advanced or metastatic solid tumors. [PDF]

J Immunother Cancer
Villano JL, Luke JJ, Julian R, Fountzilas C, Patel MR, Chisamore MJ, Bhattacharya P, Takeshita S, Soukharev S, Yamada S, Zhang L, Wentzel KP.   +11 more
europepmc   +1 more source

Opportunities, challenges, and future perspectives of oncolytic virus therapy for malignant melanoma. [PDF]

Front Immunol
Wang JW, Feng Q, Liu JH, Xun JJ.
europepmc   +1 more source

Virus, Oncolytic Virus and Human Prostate Cancer

Current Cancer Drug Targets, 2017
Prostate cancer (PCa), a disease, is characterized by abnormal cell growth in the prostate - a gland in the male reproductive system. Although older age and a family history of the disease have been recognized as the risk factors of PCa, the cause of this cancer remains unclear.
Liu, Guang Bin, Zhao, Liang, Zhang, Lifang, Zhao, Kong-Nan   +3 more
openaire   +6 more sources

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Oncolytic Virus Therapies

Pharmaceutical Patent Analyst, 2012
Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco Maria, Buonaguro, Maria Lina, Tornesello, Francesco, Izzo, Luigi, Buonaguro   +3 more
openaire   +2 more sources

Oscillations in a Spatial Oncolytic Virus Model

Bulletin of Mathematical Biology, 2023
Abstract Virotherapy treatment is a new and promising target therapy that selectively attacks cancer cells without harming normal cells. Mathematical models of oncolytic viruses have shown predator-prey like oscillatory patterns as result of an underlying Hopf bifurcation.
Arwa Abdulla Baabdulla, Thomas Hillen
openaire   +3 more sources

Oncolytic Virus Immunotherapy [PDF]

, 2022
Dear Readers, Oncolytic Viruses (OV) are self-propagating agents that can selectively induce the lysis of cancer cells while sparing normal tissues. OV-mediated cancer cell death is often immunogenic and triggers robust anticancer immune responses and ...
openaire   +2 more sources

Oncolytic Virus Therapy - Foreword

Current Cancer Drug Targets, 2007
We are very pleased and proud to be able to publish this special issue of Current Cancer Drug Targets devoted to oncolytic virus therapy covering basic and clinical research on adenovirus, vaccinia virus, herpes virus, and Newcastle disease virus. In these papers, we welcome the world's top authorities in the field who have generously contributed their
H, Kasuya, S, Takeda, S, Shimoyama, T, Shikano, N, Nomura, N, Kanazumi, S, Nomoto, H, Sugimoto, A, Nakao   +8 more
openaire   +2 more sources

Lymphomas and Oncolytic Virus Therapy

Clinical Lymphoma, 2003
There are several well-documented cases in medical literature of the remission of leukemias and malignant lymphomas following natural human viral infections. In the hope of being able to reproduce these spontaneous tumor regressions, investigators have studied various viruses with distinct oncolytic properties. The first attempts to treat patients with
Tommy, Alain, Chandini, Thirukkumaran, Donald G, Morris, Stefan J, Urbanski, Anna, Janowska-Wieczorek, Patrick W K, Lee, Anna E, Kossakowska   +6 more
openaire   +2 more sources

Oncolytic Virus Immunotherapy for Melanoma

Current Treatment Options in Oncology, 2015
Melanoma is a type of skin cancer arising from melanocytes and is increasing in incidence. Although complete surgical excision of early stage lesions may be curative, metastatic melanoma continues to be a major therapeutic challenge. Advances in understanding the molecular pathways that promote tumorigenesis and the interactions between melanoma cells ...
Neal, Dharmadhikari, Janice M, Mehnert, Howard L, Kaufman   +2 more
openaire   +2 more sources