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Oncolytic Virus Immunotherapy [PDF]
, 2022 Dear Readers, Oncolytic Viruses (OV) are self-propagating agents that can selectively induce the lysis of cancer cells while sparing normal tissues. OV-mediated cancer cell death is often immunogenic and triggers robust anticancer immune responses and ...
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Pharmaceutical Patent Analyst, 2012
Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco Maria, Buonaguro +3 more
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Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco Maria, Buonaguro +3 more
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Oscillations in a Spatial Oncolytic Virus Model
Bulletin of Mathematical Biology, 2023Abstract Virotherapy treatment is a new and promising target therapy that selectively attacks cancer cells without harming normal cells. Mathematical models of oncolytic viruses have shown predator-prey like oscillatory patterns as result of an underlying Hopf bifurcation.
Arwa Abdulla Baabdulla, Thomas Hillen
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Oncolytic Virus Therapy - Foreword
Current Cancer Drug Targets, 2007We are very pleased and proud to be able to publish this special issue of Current Cancer Drug Targets devoted to oncolytic virus therapy covering basic and clinical research on adenovirus, vaccinia virus, herpes virus, and Newcastle disease virus. In these papers, we welcome the world's top authorities in the field who have generously contributed their
H, Kasuya +8 more
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Lymphomas and Oncolytic Virus Therapy
Clinical Lymphoma, 2003There are several well-documented cases in medical literature of the remission of leukemias and malignant lymphomas following natural human viral infections. In the hope of being able to reproduce these spontaneous tumor regressions, investigators have studied various viruses with distinct oncolytic properties. The first attempts to treat patients with
Tommy, Alain +6 more
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Newcastle disease virus strain AF2240 as an oncolytic virus: A review [PDF]
Acta Tropica, 2018 The discovery of tumour selective virus-mediated apoptosis marked the birth of an alternative cancer treatment in the form of oncolytic viruses. Even though, its oncolytic efficiency was demonstrated more than 50 years ago, safety concerns which resulted
Khatijah Yusoff, Suet Lin Chia
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Oncolytic Virus Immunotherapy for Melanoma
Current Treatment Options in Oncology, 2015Melanoma is a type of skin cancer arising from melanocytes and is increasing in incidence. Although complete surgical excision of early stage lesions may be curative, metastatic melanoma continues to be a major therapeutic challenge. Advances in understanding the molecular pathways that promote tumorigenesis and the interactions between melanoma cells ...
Neal, Dharmadhikari +2 more
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Measles as a potential oncolytic virus
Reviews in Medical Virology, 2005The use of replicating viruses for cancer therapy is attracting increasing interest. Numerous viruses are now being considered as potential cancer therapeutics, including the vaccine strain of measles virus (MV). The attenuated strain of measles readily lyses transformed cells, whilst replication and lysis are limited in normal human cells.
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Journal of Biomedical Nanotechnology
Oncolytic viruses have made tremendous advances in fundamental research and clinical trials in recent years as potential anti-cancer medications. Oncolytic viruses, which are either genetically modified or naturally occurring, can kill cancer cells without harming healthy cells.
Chen Wu +3 more
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Oncolytic viruses have made tremendous advances in fundamental research and clinical trials in recent years as potential anti-cancer medications. Oncolytic viruses, which are either genetically modified or naturally occurring, can kill cancer cells without harming healthy cells.
Chen Wu +3 more
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