Results 191 to 200 of about 33,145 (233)
Some of the next articles are maybe not open access.
Oncolytic virus preclinical toxicology studies
Journal of Applied Toxicology, 2022AbstractWith the ever‐emerging concerns of patient safety during medical care, the search for treatments as safe as possible is a priority, especially when focusing on cancer treatment of which therapies often go hand in hand with severe side effects.
Agnija Rasa, Pēteris Alberts
openaire +2 more sources
Pharmaceutical Patent Analyst, 2012
Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco Maria, Buonaguro +3 more
openaire +2 more sources
Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco Maria, Buonaguro +3 more
openaire +2 more sources
Oncolytic Virus Therapy - Foreword
Current Cancer Drug Targets, 2007We are very pleased and proud to be able to publish this special issue of Current Cancer Drug Targets devoted to oncolytic virus therapy covering basic and clinical research on adenovirus, vaccinia virus, herpes virus, and Newcastle disease virus. In these papers, we welcome the world's top authorities in the field who have generously contributed their
H, Kasuya +8 more
openaire +2 more sources
Oncolytic Virus Immunotherapy for Melanoma
Current Treatment Options in Oncology, 2015Melanoma is a type of skin cancer arising from melanocytes and is increasing in incidence. Although complete surgical excision of early stage lesions may be curative, metastatic melanoma continues to be a major therapeutic challenge. Advances in understanding the molecular pathways that promote tumorigenesis and the interactions between melanoma cells ...
Neal, Dharmadhikari +2 more
openaire +2 more sources
Lymphomas and Oncolytic Virus Therapy
Clinical Lymphoma, 2003There are several well-documented cases in medical literature of the remission of leukemias and malignant lymphomas following natural human viral infections. In the hope of being able to reproduce these spontaneous tumor regressions, investigators have studied various viruses with distinct oncolytic properties. The first attempts to treat patients with
Tommy, Alain +6 more
openaire +2 more sources
Virus, Oncolytic Virus and Human Prostate Cancer
Current Cancer Drug Targets, 2017Prostate cancer (PCa), a disease, is characterized by abnormal cell growth in the prostate - a gland in the male reproductive system. Although older age and a family history of the disease have been recognized as the risk factors of PCa, the cause of this cancer remains unclear.
Liu, Guang Bin +3 more
openaire +3 more sources
Oscillations in a Spatial Oncolytic Virus Model
Bulletin of Mathematical Biology, 2023AbstractVirotherapy treatment is a new and promising target therapy that selectively attacks cancer cells without harming normal cells. Mathematical models of oncolytic viruses have shown predator-prey like oscillatory patterns as result of an underlying Hopf bifurcation.
Arwa Abdulla Baabdulla, Thomas Hillen
openaire +3 more sources
Regulatory Aspects of Oncolytic Virus Products
Current Cancer Drug Targets, 2007Many types of oncolytic viruses, wild-type virus, attenuated viruses and genetically-modified viruses, have been developed as an innovative cancer therapy. The strategies, nature, and technologies of oncolytic virus products are different from the conventional gene therapy products or cancer therapy products.
Teruhide, Yamaguchi, Eriko, Uchida
openaire +2 more sources
Oncolytic Herpes Virus Shrinks Pediatric Gliomas
Cancer Discovery, 2021Abstract In a small trial involving children with progressive high-grade gliomas, direct infusions of a genetically engineered strain of herpes simplex virus elicited responses in 11 of 12 recipients. The therapy also led to more than a doubling in average patient survival compared with historical expectations.
openaire +2 more sources