Results 171 to 180 of about 19,047 (182)
Some of the next articles are maybe not open access.
Oncolytic vaccinia virus for the treatment of cancer
Expert Opinion on Biological Therapy, 2011Gene therapy offers promising approaches for the development of anticancer agents with new modes of action. Among gene therapy vectors, vaccinia virus has emerged as an attractive agent especially when used as an oncolytic virus.This review describes the use of vaccinia virus in cancer therapy as a gene therapy vector, as an oncolytic virus and in the ...
Kilian, Guse +2 more
openaire +2 more sources
Modification of HSV-1 to an Oncolytic Virus
2014Cancer-permissive viruses or oncolytic viruses consist of either genetically engineered or naturally occurring strains that possess relatively selective replicative and/or infection abilities for cancer vs. normal cells (Chiocca, Nat Rev Cancer 2: 938-950, 2002).
Hiroshi, Nakashima, E Antonio, Chiocca
openaire +2 more sources
Oncolytic virus therapy for prostate cancer
International Journal of Urology, 2009AbstractThe use of replicationācompetent viruses that can selectively replicate in and destroy neoplastic cells is an attractive strategy for treating cancer. Various oncolytic viruses have been taken to clinical trials since a recombinant virus was first applied to cancer patients a decade ago.
Hiroshi, Fukuhara +2 more
openaire +2 more sources
Recent advances in oncolytic virus design
Clinical and Translational Oncology, 2011The cytolytic properties of viruses can be used to treat cancer. Replication of certain viruses is favoured in cancer cells, whereas others can be modified to obtain tumour specificity. This approach has evolved to become a new discipline called virotherapy.
openaire +2 more sources
Vesicular Stomatitis Virus as an Oncolytic Vector
Viral Immunology, 2004Recent data has shown that viruses such as vesicular stomatitis virus (VSV), a relatively non-pathogenic, negative-stranded RNA virus, can preferentially replicate in malignant cells and less so in normal cells. VSV appears able to carry out this function in transformed cells since these hosts exhibit the hallmarks of flawed host defense, probably ...
openaire +2 more sources
Progress in oncolytic and immunotherapy of measles virus
Minerva MedicaYongping, He +3 more
openaire +2 more sources

