Results 161 to 170 of about 19,047 (182)
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Pharmaceutical Patent Analyst, 2012
Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco Maria, Buonaguro +3 more
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Oncolytic virus (OV) therapy currently represents one of the most promising approaches to cancer treatment for their dual anticancer mechanisms: direct lysis of cancer cells (oncolytic feature) and activation of the immunosystem (cancer vaccine aspect).
Franco Maria, Buonaguro +3 more
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Oncolytic Virus Therapy - Foreword
Current Cancer Drug Targets, 2007We are very pleased and proud to be able to publish this special issue of Current Cancer Drug Targets devoted to oncolytic virus therapy covering basic and clinical research on adenovirus, vaccinia virus, herpes virus, and Newcastle disease virus. In these papers, we welcome the world's top authorities in the field who have generously contributed their
H, Kasuya +8 more
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Lymphomas and Oncolytic Virus Therapy
Clinical Lymphoma, 2003There are several well-documented cases in medical literature of the remission of leukemias and malignant lymphomas following natural human viral infections. In the hope of being able to reproduce these spontaneous tumor regressions, investigators have studied various viruses with distinct oncolytic properties. The first attempts to treat patients with
Tommy, Alain +6 more
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Virus, Oncolytic Virus and Human Prostate Cancer
Current Cancer Drug Targets, 2017Prostate cancer (PCa), a disease, is characterized by abnormal cell growth in the prostate - a gland in the male reproductive system. Although older age and a family history of the disease have been recognized as the risk factors of PCa, the cause of this cancer remains unclear.
Liu, Guang Bin +3 more
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Oncolytic Virus Immunotherapy for Melanoma
Current Treatment Options in Oncology, 2015Melanoma is a type of skin cancer arising from melanocytes and is increasing in incidence. Although complete surgical excision of early stage lesions may be curative, metastatic melanoma continues to be a major therapeutic challenge. Advances in understanding the molecular pathways that promote tumorigenesis and the interactions between melanoma cells ...
Neal, Dharmadhikari +2 more
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Oncolytic virus preclinical toxicology studies
Journal of Applied Toxicology, 2022AbstractWith the ever‐emerging concerns of patient safety during medical care, the search for treatments as safe as possible is a priority, especially when focusing on cancer treatment of which therapies often go hand in hand with severe side effects.
Agnija Rasa, Pēteris Alberts
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Measles as a potential oncolytic virus
Reviews in Medical Virology, 2005The use of replicating viruses for cancer therapy is attracting increasing interest. Numerous viruses are now being considered as potential cancer therapeutics, including the vaccine strain of measles virus (MV). The attenuated strain of measles readily lyses transformed cells, whilst replication and lysis are limited in normal human cells.
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Journal of Biomedical Nanotechnology
Oncolytic viruses have made tremendous advances in fundamental research and clinical trials in recent years as potential anti-cancer medications. Oncolytic viruses, which are either genetically modified or naturally occurring, can kill cancer cells without harming healthy cells.
Chen Wu +3 more
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Oncolytic viruses have made tremendous advances in fundamental research and clinical trials in recent years as potential anti-cancer medications. Oncolytic viruses, which are either genetically modified or naturally occurring, can kill cancer cells without harming healthy cells.
Chen Wu +3 more
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Regulatory Aspects of Oncolytic Virus Products
Current Cancer Drug Targets, 2007Many types of oncolytic viruses, wild-type virus, attenuated viruses and genetically-modified viruses, have been developed as an innovative cancer therapy. The strategies, nature, and technologies of oncolytic virus products are different from the conventional gene therapy products or cancer therapy products.
Teruhide, Yamaguchi, Eriko, Uchida
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Measles Virus as An Oncolytic Vector Platform
Current Gene Therapy, 2008Viral vector systems are widely being used in the development of new genetic approaches for a variety of human diseases. Oncolytic viruses have shown great potential as cancer therapeutics. The ideal viral vector for cancer gene therapy eradicates a clinically significant fraction of malignant cells and leaves normal tissues unharmed.
B, Blechacz, S J, Russell
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