Results 231 to 240 of about 31,178 (269)
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Oncolytic Viruses: Whats Next?
Current Cancer Drug Targets, 2007Cancer is a complex disease that often eludes successful treatment due to its propensity to evolve or adapt in the face of current therapeutic regimes. It is reasonable to suggest that sophisticated therapeutics that can attack cancers in multiple, but targeted ways, will be necessary in order to improve current success rates.
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Oncolytic Viruses: Programmable Tumour Hunters
Current Gene Therapy, 2002Despite significant improvements in early detection and refinements of therapeutic protocols over the last several decades, cancer remains one of the leading causes of death in North America. In particular, treatment of metastatic cancers is a highly desirable and yet still elusive goal of the oncologist.
J C, Bell +3 more
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Oncolytic viruses and cancer therapy
Cytokine & Growth Factor Reviews, 2001In the hopes that a better understanding of cancer biology would allow for the development of novel, more effective therapeutics, a concerted effort over the past 20 years has focussed on the molecular mechanisms of cell growth control and tumorigenesis.
K L, Norman, F, Farassati, P W, Lee
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Current opinion in molecular therapeutics, 2006
Naturally oncolytic viruses are replication-competent viruses that have an innate ability to selectively infect and kill tumor cells. Despite being used in the original attempts to treat cancer with live viruses five decades ago, interest in naturally oncolytic viruses has lagged behind the support for engineered adenoviruses and herpesviruses as ...
M Scot, Roberts +3 more
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Naturally oncolytic viruses are replication-competent viruses that have an innate ability to selectively infect and kill tumor cells. Despite being used in the original attempts to treat cancer with live viruses five decades ago, interest in naturally oncolytic viruses has lagged behind the support for engineered adenoviruses and herpesviruses as ...
M Scot, Roberts +3 more
openaire +1 more source
Cancer Treatment Involving Oncolytic Viruses
Clinical Lung Cancer, 1999Viruses capable of inducing lysis of malignant cells through their replication process are known as "oncolytic" viruses. Clinical trials in oncology have been performed with oncolytic viruses for nearly fifty years. Both systemic and intratumoral routes of administration have been explored.
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Transmissibility and transmission of respiratory viruses
Nature Reviews Microbiology, 2021Nancy H L Leung
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Revisiting the rules of life for viruses of microorganisms
Nature Reviews Microbiology, 2021Adrienne M S Correa +2 more
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