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Oncolytic Viruses as a Novel Therapeutic Approach for Colorectal Cancer: Mechanisms, Current Advances, and Future Directions. [PDF]

open access: yesCancers (Basel)
Pérez-Domínguez F   +4 more
europepmc   +1 more source
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Oncolytic viruses

Nature Reviews Cancer, 2002
Although the cytotoxic effects of viruses are usually viewed in terms of pathogenicity, it is possible to harness this activity for therapeutic purposes. Viral genomes are highly versatile, and can be modified to direct their cytotoxicity towards cancer cells. These viruses are known as oncolytic viruses.
E Antonio Chiocca
exaly   +4 more sources

Developing oncolytic viruses for clinical use: A consortium approach [PDF]

open access: yesCytokine and Growth Factor Reviews, 2020
The use of oncolytic viruses forms an appealing approach for cancer treatment. On the one hand the viruses replicate in, and kill, tumor cells, leading to their intra-tumoral amplification.
Vera Kemp   +2 more
exaly   +4 more sources

Oncolytic Viruses and Cancer Immunotherapy

Current Oncology Reports, 2022
Oncolytic viruses (OVs) exert their antitumor effect through selective killing of cancer cells and induction of host anti-tumor immunity. This review aims to summarize the recent and current trials with OVs for the treatment of lung cancer.Several OVs have been developed for the treatment of lung cancer including adenovirus, coxsackievirus B3, reovirus,
Jyoti, Malhotra, Edward S, Kim
openaire   +2 more sources

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