Results 241 to 250 of about 490,236 (289)

Gut microbiome and plasma metabolic signatures of one-carbon metabolism differentiate oedematous and non-oedematous severe acute malnutrition

Robertson RC, Edens TJ, Baharmand I, Varankovich N, Dumbura C, Panchal M, Mutasa K, Ntozini R, Chasekwa B, Mwakamui S, Francis F, Besa E, Runodamoto T, Ngosa D, Majo FD, Zyambo K, Bourke CD, Rukobo S, Govha M, Amadi B, Nathoo K, Bwakura-Dangarembizi M, Swann JR, Kelly P, Manges AR, Prendergast AJ.   +25 more
europepmc   +1 more source

Mitochondrial One-Carbon Metabolism Drives CD34-Lineage Cells to Differentiate Into T Follicular Helper Cells to Form Tertiary Lymphoid Organs in Transplant Arteriosclerosis. [PDF]

Circulation
Sun X, Wu J, He T, Yao M, Qin L, Weng C, Peng L, Xiao Q, Lu Y, Yuan H, Xu Q, Cai J.   +11 more
europepmc   +1 more source

Experimental Environment Is a Determinant of Gene Methylation and One-Carbon Metabolism in Obese Adult Mice.

Lifestyle Genom
Yang Z, Kubant R, Kranenburg E, Cho CE, Anderson GH.   +4 more
europepmc   +1 more source

One-carbon metabolism-related compounds are associated with epigenetic aging biomarkers: results from the cross-sectional National Health and Nutrition Examination Survey 1999-2002. [PDF]

Am J Clin Nutr
Bozack AK, Khodasevich D, Nwanaji-Enwerem JC, Gladish N, Shen H, Daredia S, Gamble M, Needham BL, Rehkopf DH, Cardenas A.   +9 more
europepmc   +1 more source

DHFR2 RNA directly regulates dihydrofolate reductase and its expression level impacts folate one carbon metabolism. [PDF]

FASEB J
Drago P, Bookey N, Leung KY, Henry M, Meleady P, Greene NDE, Parle-McDermott A.   +6 more
europepmc   +1 more source

DNA Methylation change in genes involved in Alcohol metabolism (ALDH2) and One-carbon metabolism (MTHFR) pathways among people with Alcohol Use Disorder

Shankarappa B, Mahadevan J, Viswanath B, Devarbhavi H, Murthy P, Jain S, Purushottam M.   +6 more
europepmc   +1 more source

One-carbon metabolism and epigenetics

Molecular Aspects of Medicine, 2017
The function of one-carbon metabolism is that of regulating the provision of methyl groups for biological methylation reactions including that of DNA and histone proteins. Methylation at specific sites into the DNA sequence and at histone tails are among the major epigenetic feature of mammalian genome for the regulation of gene expression. The enzymes
Simonetta Friso, Silvia Udali, Domenica De Santis   +2 more
exaly   +5 more sources

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Serine and one-carbon metabolism in cancer

Nature Reviews Cancer, 2016
The non-essential amino acid serine supports several metabolic processes that are crucial for the growth and survival of proliferating cells, including protein, amino acid and glutathione synthesis. As an important one-carbon donor to the folate cycle, serine contributes to nucleotide synthesis, methylation reactions and the generation of NADPH for ...
Karen H Vousden, Vousden Karen H
exaly   +3 more sources

Gene-Nutrient Interactions in One-Carbon Metabolism

Current Drug Metabolism, 2005
Advances in molecular biology greatly contributed, in the past decades, to a deeper understanding of the role of gene function in disease development. Environmental as well as nutritional factors are now well acknowledged to interact with the individual genetic background for the development of several diseases, including cancer, cardiovascular disease,
FRISO, Simonetta, S.W. Choi
openaire   +4 more sources