Results 61 to 70 of about 341,624 (160)

The role of B12 deficiency and methionine synthase in methionine-dependent cancer cells

Cancer & Metabolism
Background Human cells can synthesize methionine from homocysteine and folate-coupled methyl groups via the B12-dependent enzyme methionine synthase (MTR).
Mohamed M. A. El Husseiny, Roland Nilsson   +1 more
doaj   +1 more source

Association of neural tube defects with maternal alterations and genetic polymorphisms in one-carbon metabolic pathway

Italian Journal of Pediatrics, 2019
Background Neural tube defects (NTDs) are birth defects of the brain, spine, or spinal cord invoked by the insufficient intake of folic acid in the early stages of pregnancy and have a complex etiology involving both genetic and environmental factors. So
Chun-Quan Cai, Yu-Lian Fang, Jian-Bo Shu, Lin-Sheng Zhao, Rui-Ping Zhang, Li-Rong Cao, Yi-Zheng Wang, Xiu-Fang Zhi, Hua-Lei Cui, Ou-Yan Shi, Wei Liu   +10 more
doaj   +1 more source

Tissue-Specific Mitochondrial Functionality and Mitochondrial-Related Gene Profiles in Response to Maternal Nutrition and One-Carbon Metabolite Supplementation During Early Pregnancy in Heifers

Animals
Background: Mitochondria are essential for fetal development, regulating energy metabolism and metabolic programming. This study examined how maternal nutrition and one-carbon metabolite (OCM) supplementation during early gestation affect mitochondrial ...
Kazi Sarjana Safain, Matthew S. Crouse, Mara R. Hirchert, Yssi L. Entzie, Jessica G. Syring, Mojtaba Daneshi, Muhammad Anas, Layla E. King, Lawrence P. Reynolds, Pawel P. Borowicz, Carl R. Dahlen, Alison K. Ward, Joel S. Caton, Kendall C. Swanson   +13 more
doaj   +1 more source

One-carbon metabolism in RCC [PDF]

Nature Reviews Urology, 2019
openaire   +2 more sources

Dietary nutrients involved in one-carbon metabolism and colorectal cancer risk

LabMed Discovery
Objective: Colorectal cancer (CRC), a common malignant tumor of the digestive tract, poses a worldwide threat to human health. Methods: This study conducted a narrative literature review to assess and provide perspectives on the evolving understanding of
Lin Deng, Yu-chan Huang-fu, Yan-hui Ma
doaj   +1 more source

Folate and vitamin B12 supplementation in patients with schizophrenia and low serum folate level: A 24-week randomized, double-blind, placebo-controlled study

Journal of the Formosan Medical Association
Purpose: We aimed to evaluate the effects of folate and vitamin B12 on psychopathology in patients with schizophrenia and low serum folate levels. Methods: Fifty-five schizophrenia patients with serum folate levels lower than 6 mg/L were randomized in a ...
Chun-Hsin Chen, Chih-Chiang Chiu, Yi-Hang Chiu, Chin-Hao Chang, Yu-Han Chang, Ming-Chyi Huang, Mong-Liang Lu, Po-Yu Chen   +7 more
doaj   +1 more source

Modulating One-Carbon Metabolism with B-Vitamins to Protect the Retinal Barrier and Prevent Retinal Degeneration. [PDF]

Nutrients
Abouhish H, Shalaby L, Elzayat O, Peddireddy N, Tawfik A.   +4 more
europepmc   +1 more source

The Interplay of One-Carbon Metabolism, Mitochondrial Function, and Developmental Programming in Ruminant Livestock. [PDF]

J Dev Biol
Safain KS, Swanson KC, Caton JS.
europepmc   +1 more source

Tyrosine phosphorylation coupling of one-carbon metabolism and virulence in an endogenous pathogen. [PDF]

Proc Natl Acad Sci U S A
Stocke KS, Pandey SD, Jin S, Perpich JD, Yakoumatos L, Kosaki H, Wilkey DW, Fitzsimonds ZR, Vashishta A, Snider I, Sriwastva MK, Li H, Jin JZ, Miller DP, Merchant ML, Bagaitkar J, Uriarte SM, Potempa J, Lamont RJ.   +18 more
europepmc   +1 more source

One-Carbon Metabolism and Midbrain Dopaminergic Cells in Lesch-Nyhan Disease. [PDF]

Mol Syndromol
Alsuwaidi S, Ernst C.
europepmc   +1 more source