Results 41 to 50 of about 20,326,114 (289)
One-carbon metabolism metabolite levels at T0 and T1 (n = 67).
, 2019 One-carbon metabolism metabolite levels at T0 and T1 (n = 67).
Bertrand D. van Zelst (7392497) +8 more
core +1 more source
Chromium induced neurotoxicity by altering metabolism in zebrafish larvae
Ecotoxicology and Environmental Safety, 2021 Background: Recently, both trivalent chromium Cr (III) and hexavalent chromium Cr (VI) have been reported to produce neurotoxicity. However, the underlying mechanisms of the neurotoxicity caused by different chemical valence of chromium remain unclear ...
Yawen Xu +6 more
doaj +1 more source
Carbon metabolism of enterobacterial human pathogens growing in epithelial colorectal adenocarcinoma (Caco-2) cells. [PDF]
, 2010 Analysis of the genome sequences of the major human bacterial pathogens has provided a large amount of information concerning their metabolic potential.
Götz Andreas +12 more
core +2 more sources
eLifeCellular metabolism plays an essential role in the regrowth and regeneration of a neuron following physical injury. Yet, our knowledge of the specific metabolic pathways that are beneficial to neuron regeneration remains sparse. Previously, we have shown
Dilip Kumar Yadav +4 more
doaj +1 more source
BiomedicinesS-adenosylmethionine (SAM) and S-adenosylhomocysteine (SAH) are essential intermediates in one-carbon metabolism and key regulators of cellular methylation capacity. Their concentrations and the SAM/SAH ratio are increasingly studied as biomarkers across
Antonina Kuty +3 more
doaj +1 more source
Metabolic responses of primary and transformed cells to intracellular Listeria monocytogenes. [PDF]
, 2012 The metabolic response of host cells, in particular of primary mammalian cells, to bacterial infections is poorly understood. Here, we compare the carbon metabolism of primary mouse macrophages and of established J774A.1 cells upon Listeria monocytogenes
Wolfgang Eisenreich (108576) +19 more
core +1 more source
Nature Communications, 2023 Flavin containing monooxygenase 2 (FMO-2) is known to increase lifespan under dietary restriction through incompletely understood mechanisms. Here the authors report that FMO-2 modifies tryptophan and methionine metabolic pathways to enhance stress ...
Hyo Sub Choi +14 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
One-carbon metabolism and ionizing radiation: a multifaceted interaction
Biomolecular Concepts, 2017 Ionizing radiation (IR) is a ubiquitous component of our environment and an important tool in research and medical treatment. At the same time, IR is a potent genotoxic and epigenotoxic stressor, exposure to which may lead to negative health outcomes ...
Miousse Isabelle R. +7 more
doaj +1 more source
Cell Death and Disease, 2023 Anaplastic thyroid cancer (ATC) is one of the most aggressive tumors with an extremely poor prognosis. Based on the several biological features related to glutamine metabolism in ATC, we hypothesized glutaminolysis inhibition induces cell death in ATC ...
Yeseong Hwang +8 more
doaj +1 more source