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Preconception One‐Carbon Metabolism Nutrient Levels in Preparing for Pregnancy Couples and Spontaneous Pregnancy Loss: A Prospective Cohort Study [PDF]
MedCommSpontaneous pregnancy loss (SPL) remains an important yet poorly understood pregnancy outcome. One‐carbon metabolism (OCM) nutrients play an essential role in embryonic development, but their relationship with SPL remains unclear.
Xiaotian Chen +18 more
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Treating dysfunctional one-carbon metabolism in glaucoma [PDF]
Neural Regeneration ResearchJames R. Tribble, Pete A. Williams
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Serine and one-carbon metabolisms bring new therapeutic venues in prostate cancer
Discover Oncology, 2021 Serine and one-carbon unit metabolisms are essential biochemical pathways implicated in fundamental cellular functions such as proliferation, biosynthesis of important anabolic precursors and in general for the availability of methyl groups.
Carlo Ganini +14 more
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Progress in One-carbon Metabolism and Tumor Therapy
Zhongliu Fangzhi Yanjiu, 2021 In recent years, it has already run into a common view that "tumor is a metabolic disease", and the reprogramming of tumor metabolism has become the focus of current research.
CHAI Dongqi, WANG Weixing
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One carbon metabolism in SAR11 pelagic marine bacteria. [PDF]
PLoS ONE, 2011 The SAR11 Alphaproteobacteria are the most abundant heterotrophs in the oceans and are believed to play a major role in mineralizing marine dissolved organic carbon.
Jing Sun +7 more
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One‐carbon metabolism, folate, zinc and translation
Microbial Biotechnology, 2020 Summary The translation process, central to life, is tightly connected to the one‐carbon (1‐C) metabolism via a plethora of macromolecule modifications and specific effectors. Using manual genome annotations and putting together a variety of experimental
Antoine Danchin +2 more
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The toxic side of one-carbon metabolism and epigenetics
Redox Biology, 2021 One-carbon metabolism is a central metabolic hub that provides one-carbon units for essential biosynthetic reactions and for writing epigenetics marks.
Agustín E. Morellato +2 more
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One-Carbon and Polyamine Metabolism as Cancer Therapy Targets
Biomolecules, 2022 Cancer metabolic reprogramming is essential for maintaining cancer cell survival and rapid replication. A common target of this metabolic reprogramming is one-carbon metabolism which is notable for its function in DNA synthesis, protein and DNA ...
Anowarul Islam +3 more
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One-carbon metabolism during the menstrual cycle and pregnancy.
PLoS Computational Biology, 2021 Many enzymes in one-carbon metabolism (OCM) are up- or down-regulated by the sex hormones which vary diurnally and throughout the menstrual cycle. During pregnancy, estradiol and progesterone levels increase tremendously to modulate physiological changes
Ruby Kim +2 more
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The Impact of One Carbon Metabolism on Histone Methylation
Frontiers in Genetics, 2019 The effect of one carbon metabolism on DNA methylation has been well described, bridging nutrition, metabolism, and epigenetics. This modification is mediated by the metabolite S-adenosyl methionine (SAM), which is also the methyl-donating substrate of ...
Magdalini Serefidou +2 more
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