Results 81 to 90 of about 18,461,677 (262)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Uncertainty of One-Dimensional Consolidation of Multi-Layered Soft Clay Soils
, 2011 The measured coefficient of consolidation can have a substantial degree of variation even in a uniform clay layer. The probability characteristic values for such parameters as consolidation coefficient and compression modulus are analyzed from local ...
Xiao Yong Li
core +1 more source
Analytical and Numerical Modelling of One-Dimensional Consolidation of Stabilized Peat [PDF]
, 2019 The objective of the paper is to compare and evaluate analytical and numerical solutions of one-dimensional consolidation of stabilized peat. The type of analytical method used to solve the problem is exact method by separation of variables and ...
Somanathan, Shamini, Wong, Leong Sing
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Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer
Molecular Oncology, EarlyView.Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley +1 more source
Molecular Oncology, EarlyView.We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober +16 more
wiley +1 more source
One-dimensional consolidation of clay
, 1966 This study has developed a rheological model capable of accounting for all the significant characteristics exhibited by saturated clays in one-dimensional consolidation.
Desai, C. S. (Chandrakant S.), 1936-
core
Analytical Solutions of Linear Finite-Strain One-Dimensional Consolidation
, 2002 Numerical solutions of linear finite-strain one-dimensional consolidation of both initially unconsolidated and initially fully consolidated soil layers with both one-way and two-way drainage have been available for some time. However, no solutions of the
Morris, P. H.
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One-Dimensional Consolidation Characteristics and Mechanisms of Soft Soil Under Surcharge Preloading
Applied SciencesThis study investigates staged surcharge preloading at a coastal test section by integrating field monitoring (pore-water pressure, settlement/settlement rate, and layer-by-layer deformation) with laboratory consolidation tests and field vane shear ...
Pan Zhao +6 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source