Tandem aza-Claisen rearrangement and ring closing metathesis reactions: the stereoselective synthesis of functionalised carbocyclic amides [PDF]
, 2009 A one-pot, tandem process has been developed for the efficient synthesis of functionalised carbocyclic amides. A substituted cyclopentenyl trichloroacetamide was synthesised using a tandem thermal aza-Claisen rearrangement and RCM process, while an ...
Donaldson, A. +2 more
core +1 more source
One-Pot Reductive Acetylation of Aldehydes using 1-Hydrosilatrane in Acetic Acid
SynOpen, 2019 A one-pot, direct reductive acetylation of aldehydes was achieved under mild conditions using 1-hydrosilatrane as a safe and easily accessible catalyst.
Reuben R. James +6 more
doaj +1 more source
Facile one-pot synthesis of amoxicillin-coated gold nanoparticles and their antimicrobial activity [PDF]
, 2014 Nanomaterials have been the object of intense study due to promising applications in a number of different disciplines. In particular, medicine and biology have seen the potential of these novel materials with their nanoscale properties for use in ...
A Fleming +19 more
core +1 more source
Asymmetric one-pot synthesis of cyclopropanes
Macedonian Journal of Chemistry and Chemical Engineering, 2016 Cycloaddition of the diazoalkanes to electron-deficient olefins (in situ) affords polysubstituted cyclopropanes in high yields (up to 85%). Deprotection of the ketal protecting group provided water-soluble cyclopropane-bearing carbohydrate in good yields.
Naoufel Ben Hamadi +2 more
doaj +1 more source
Room-Temperature Alternative to the Arbuzov Reaction: The Reductive Deoxygenation of Acyl Phosphonates [PDF]
, 2010 The reductive deoxygenation of acyl phosphonates using a Wolff−Kishner-like sequence is described. This transformation allows direct access to alkyl phosphonates from acyl phosphonates at room temperature. The method can be combined with acyl phosphonate
Dougherty, Dennis A. +1 more
core +2 more sources
One-pot preparation of substituted pyrroles from α-diazocarbonyl compounds
Beilstein Journal of Organic Chemistry, 2008 In this work an efficient one-pot synthesis of substituted pyrroles 7a–n is described, which involves the in situ formation of dihydrofurans ethyl 5-butoxy-2-methyl-4,5-dihydrofuran-3-carboxylate (4), 1-(5-butoxy-2-methyl-4,5-dihydrofuran-3-yl)ethanone ...
Fernando de C. da Silva +5 more
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Hept-6-en-1-yl Furan-2-carboxylate
MolbankThis study aims to develop an efficient and green one-pot method for the synthesis of 6-en-1-yl furan-2-carboxylic acid heptyl ester. Initially, using furfural as the starting substrate, hept-6-en-1-yl furan-2-carboxylate was prepared using a one-pot ...
Zhongwei Wang, Lin Song, Yukun Qin
doaj +1 more source
Highly efficient methods for the one-pot synthesis of b-substituted enones [PDF]
, 2006 A mild and practically-convenient one-pot procedure for the direct b-substitution of enones has been developed using a conjugate addition–oxidation strategy with a full range of copper-based reagents and N-tert-butylphenylsulfinimidoyl chloride; alkyl ...
Bartoli +29 more
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Improved synthesis and in vitro study of antimicrobial activity of α,β-unsaturated and α-bromo carboxylic acids [PDF]
Journal of the Serbian Chemical Society, 2012 A series of α,β-unsaturated and α-bromo carboxylic acids were identified as potent antimicrobial agents. Antimicrobial activity was evaluated using broth microdilution method.
Vitnik Vesna D. +4 more
doaj +1 more source
Organics, 2023 (E)-1-aryl-2,4-bis(trimethylsilyl)but-1-en-3-ynes readily undergo protodesilylation and subsequent aerobic, copper-free Sonogashira cross-coupling with aryl halides to form (E)-1,4-diaryl-2-(trimethylsilyl)but-1-en-3-ynes.
Szymon Rogalski +2 more
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