Results 111 to 120 of about 4,597,300 (303)

Onset of dendritic flux avalanches in superconducting films

open access: yes, 2006
We report a detailed comparison of experimental data and theoretical predictions for the dendritic flux instability, believed to be a generic behavior of type-II superconducting films.
A. A. F. Olsen   +10 more
core   +1 more source

Redox regulation meets metabolism: targeting PRDX2 to prevent hepatocellular carcinoma

open access: yesMolecular Oncology, EarlyView.
PRDX2 acts as a central redox hub linking metabolic dysfunction‐associated steatohepatitis (MASH) to hepatocellular carcinoma (HCC). In normal hepatocytes, PRDX2 maintains redox balance and metabolic homeostasis under oxidative stress. In contrast, during malignant transformation, PRDX2 promotes oncogenic signaling, stemness, and tumor initiation ...
Naroa Goikoetxea‐Usandizaga   +2 more
wiley   +1 more source

Evaluating a Method to Estimate Mediation Effects With Discrete-Time Survival Outcomes

open access: yesFrontiers in Psychology, 2019
The utility of evaluating mediation effects spans across research domains. The model facilitates investigation of underlying mechanisms of event timing and, as such, has the potential to help strengthen etiological research and inform intervention work ...
Amanda Jane Fairchild   +5 more
doaj   +1 more source

Onset of magnetism in B2 transition metals aluminides

open access: yes, 1998
Ab initio calculation results for the electronic structure of disordered bcc Fe(x)Al(1-x) (0 ...
A. Amamou   +56 more
core   +1 more source

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Fronts Propagation at the Onset of Plastic Yielding

open access: yes, 2008
The existence of a finite threshold, the yield stress, for the onset of plastic yielding is a universal feature of plasticity. This jamming-unjamming transition is naturally accounted for by the dynamics of a bistable internal state field.
Bouchbinder, Eran, Lo, Ting-Shek
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

open access: yesMolecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos   +6 more
wiley   +1 more source

The Impact of Bulbar and Upper Motor Neuron Involvement on Oculomotor Movement in Amyotrophic Lateral Sclerosis

open access: yesBrain and Behavior
Background Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease characterized by the degeneration of both lower and upper motor neurons (UMN).
Dongchao Shen   +5 more
doaj   +1 more source

Diamagnetism and Cooper pairing above $T_c$ in cuprates

open access: yes, 2009
In the cuprate superconductors, Nernst and torque magnetization experiments have provided evidence that the disappearance of the Meissner effect at $T_c$ is caused by the loss of long-range phase coherence, rather than the vanishing of the pair ...
Ando, Yoichi   +6 more
core   +1 more source

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