Results 71 to 80 of about 4,617,678 (304)

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Conduction at the onset of chaos

, 2017
After a general discussion of the thermodynamics of conductive processes, we introduce specific observables enabling the connection of the diffusive transport properties with the microscopic dynamics.
Baldovin, Fulvio
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Predictors of Success in Horizontal Strabismus Surgery: Insights from a Prospective Study

Juxta: Jurnal Ilmiah Mahasiswa Kedokteran Universitas Airlangga
Introduction: Strabismus is an eye disorder characterized by misalignment of the eyes, which can occur in individuals of any age. This study explored the surgical outcomes of horizontal strabismus correction in patients, aiming to provide insights into ...
Aurellia Valmai Tjujitno, Reni Prastyani, Joni Susanto, Rozalina Loebis, Luki Indriaswati, Lely Retno Wulandari   +5 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

FEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Practical application of real-time sub-seasonal monsoon onset forecasting and monitoring for decision-making

Frontiers in Climate
Skilful monsoon onset forecasts are highly sought after in West Africa, due to the importance of monsoon onset for supporting agriculture, disease prevalence and energy provision.
Elisabeth M. Thompson, Elisabeth M. Thompson, Elisabeth M. Thompson, Caroline M. Wainwright, Caroline M. Wainwright, Caroline M. Wainwright, Linda C. Hirons, Linda C. Hirons, Steven J. Woolnough, Steven J. Woolnough   +9 more
doaj   +1 more source

Detecting Rainfall Onset Using Sky Images

, 2016
Ground-based sky cameras (popularly known as Whole Sky Imagers) are increasingly used now-a-days for continuous monitoring of the atmosphere. These imagers have higher temporal and spatial resolutions compared to conventional satellite images.
Dev, Soumyabrata, Lee, Yee Hui, Manandhar, Shilpa, Winkler, Stefan   +3 more
core   +1 more source

A High‐Sensitivity Circulating Nucleic Acid Sequencing Assay for Assessing Treatment Response to Alectinib in a Pediatric Patient With ALK‐Rearranged Non–Small Cell Lung Cancer

Pediatric Blood &Cancer, EarlyView.
Alberto D. Guerra, Nicholas F. Evageliou, Vandana Batra, Kristen L. Dalton, Stephanie Ortel, Usman Ashraf, Tricia R. Bhatti, Lisa J. States, Lea F. Surrey, Theodore W. Laetsch   +9 more
wiley   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Contrasting Pressure Effects in Sr2VFeAsO3 and Sr2ScFePO3

, 2009
We report the resistivity measurements under pressure of two Fe-based superconductors with a thick perovskite oxide layer, Sr2VFeAsO3 and Sr2ScFePO3. The superconducting transition temperature Tc of Sr2VFeAsO3 markedly increases with increasing pressure.
Gooch M., Gooch M., Hamlin J. J., Igawa K., Imai T., Kamihara Y., Kamihara Y., Kito H., Kobayashi T. C., Kotegawa H., Kumai R., Kuroki K., Lee C.-H., Margadonna S., Margadonna S., Masaki S., Medvedev S., Mito M., Mizuguchi Y., Murata K., Ogino H., Ogino H., Pitcher M. J., Ren Z.-A., Rotter M., Rotter M., Shein I. R., Shein I. R., Takahashi H., Takeshita N., Tegel M., Zhu X.   +31 more
core   +1 more source