Results 151 to 160 of about 229,442 (394)

Ontogeny in the Family

open access: yesBehavior Genetics, 2005
When ontogeny takes place in a family, and parents provide essential resources for development, the parents become an environmental component to the development of a wide range of offspring traits. Because differences among parents may partly reflect genetic variation, this environmental component contains genes and may itself evolve.
openaire   +4 more sources

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

open access: yesFEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

The Machine Conception of the Organism in Development and Evolution: A Critical Analysis [PDF]

open access: yes, 2014
This article critically examines one of the most prevalent metaphors in modern biology, namely the machine conception of the organism (MCO). Although the fundamental differences between organisms and machines make the MCO an inadequate metaphor for ...
Nicholson, Daniel J.
core  

5.3 Ontogeny of T-cell surface molecules and receptors in the thymus [PDF]

open access: green, 1992
Marie Paule Defresne   +9 more
openalex   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

open access: yesFEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Methylmercury Interactions With Gut Microbiota and Potential Modulation of Neurogenic Niches in the Brain

open access: yesFrontiers in Neuroscience, 2020
Daniel V. Pinto   +5 more
doaj   +1 more source

Anatomia e ontogênese da sâmara de Centrolobium tomentosum Guill. ex Benth. (Leguminosae: Papilionoideae)

open access: yesRodriguésia
RESUMO Dalbergieae é considerada uma tribo basal de Papilionoideae (Leguminosae) e apresenta grande variação carpológica; apesar disso, poucos trabalhos analisam detalhadamente os órgãos reprodutivos destas plantas. O presente estudo teve como objetivo a
Denise Maria Trombert Oliveira   +2 more
doaj   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

open access: yesFEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang   +9 more
wiley   +1 more source

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