Results 101 to 110 of about 885,759 (298)

An Approach to Cope with Ontology Changes for Ontology-based Applications

open access: yes, 2006
Keeping track of ontology changes is becoming a critical issue for ontology-based applications because updating an ontology that is in use may result in inconsistencies between the ontology and the knowledge base, dependent ontologies and dependent ...
Alani, Harith   +3 more
core  

Facets, Tiers and Gems: Ontology Patterns for Hypernormalisation [PDF]

open access: yes, 2017
There are many methodologies and techniques for easing the task of ontology building. Here we describe the intersection of two of these: ontology normalisation and fully programmatic ontology development.
Lord, Phillip, Stevens, Robert
core   +1 more source

Ontologies and Ontological Representation

open access: yesOvidius University Annals: Economic Sciences Series, 2020
The present paper aims to present the main theoretical and practical aspects of what ontology and knowledge bases mean, having the role of providing as precise information as possible. Ontologies are considered to be a vocabulary of concepts, and the purpose of this "vocabulary" is to ensure a semantically based level of knowledge based on semantics in
Tudor Colomeischi, Eugenia Iancu
openaire   +1 more source

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

open access: yesFEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li   +6 more
wiley   +1 more source

OntoMaven: Maven-based Ontology Development and Management of Distributed Ontology Repositories [PDF]

open access: yes, 2013
In collaborative agile ontology development projects support for modular reuse of ontologies from large existing remote repositories, ontology project life cycle management, and transitive dependency management are important needs.
Paschke, Adrian
core  

The Plant Ontology™ Consortium and Plant Ontologies [PDF]

open access: yesComparative and Functional Genomics, 2002
AbstractThe goal of the Plant Ontology™ Consortium is to produce structured controlled vocabularies, arranged in ontologies, that can be applied to plant‐based database information even as knowledge of the biology of the relevant plant taxa (e.g. development, anatomy, morphology, genomics, proteomics) is accumulating and changing.
openaire   +2 more sources

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

The bilocated mind: New perspectives on self-localization and self-identification

open access: yesFrontiers in Human Neuroscience, 2013
Does the human mind allow for self-locating at more than one place at a time? Evidence from neurology, cognitive neuroscience, and experimental psychology suggests that mental bilocation is a complex, but genuine experience, occurring more frequently ...
Tiziano eFurlanetto   +2 more
doaj   +1 more source

EXPLORING ONTOLOGIES

open access: yes, 2001
Ontologies are studied by many scholars with diverse backgrounds and are applied in a variety of contexts and application areas. Despite the numerous reviews published there are many issues which still remain unclear with respect to their cost-effective deployment, identification of tradeoffs, maintenance strategies and ways of integration. Furthermore,
openaire   +3 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

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