Results 111 to 120 of about 1,038,617 (321)
FEBS Open Bio, EarlyView.Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li +8 more
wiley +1 more source
The Role of Foundational Relations in the Alignment of Biomedical Ontologies [PDF]
, 2004 The Foundational Model of Anatomy (FMA) symbolically represents the structural organization of the human body from the macromolecular to the macroscopic levels, with the goal of providing a robust and consistent scheme for classifying anatomical entities
Rosse, Cornelius, Smith, Barry
core +1 more source
Ontology Alignment for Accurate Ontology Matching: A Survey
, 2023 AbstractEdge computing, a distributed computing architecture within the knowledge-defined network (KDN), faces challenges due to the significant disparities and data heterogeneity among its nodes, hindering their interaction. Ontology, a solution within the Semantic Web, is well-suited for addressing data heterogeneity and matching ontologies ...
Hasham Khan +4 more
openaire +1 more source
FEBS Open Bio, EarlyView.Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Augmenting Ontology Alignment by Semantic Embedding and Distant Supervision
Extended Semantic Web Conference, 2021 Jiaoyan Chen +5 more
semanticscholar +1 more source
Arthritis Care &Research, EarlyView.Objective A leading cause of death among patients with scleroderma (SSc), interstitial lung disease (ILD) remains challenging to prognosticate. The discovery of biomarkers that accurately determine which patients would benefit from close monitoring and aggressive therapy would be an essential clinical tool.
Cristina M. Padilla +13 more
wiley +1 more source
CroMatcher 2.0: A Comprehensive Analysis of the Improved Ontology Matching System
IEEE AccessOne of the main challenges in ontology matching is to match ontologies with high accuracy. Therefore, ontology matching systems typically use multiple basic matchers, each targeting a specific ontology component for the matching process.
Marko Gulic +2 more
doaj +1 more source
Advanced Engineering Materials, EarlyView.The documentation of component manufacture has become an essential part of today's production processes, especially for the analysis and optimization of production or component design with regard to structural performance, economic efficiency, and sustainability.
Björn Denker +4 more
wiley +1 more source