Results 51 to 60 of about 1,038,617 (321)

Ontology alignment in the biomedical domain using entity definitions and context [PDF]

Workshop on Biomedical Natural Language Processing, 2018
Ontology alignment is the task of identifying semantically equivalent entities from two given ontologies. Different ontologies have different representations of the same entity, resulting in a need to de-duplicate entities when merging ontologies.
Lucy Lu Wang, Chandra Bhagavatula, Mark Neumann, Kyle Lo, Christopher Wilhelm, Bridger Waleed Ammar   +5 more
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

Journal Staff [PDF]

, 1939
With the proliferation of ontologies and their use in semantically-enabled applications, the issue of finding and repairing defects in ontologies has become increasingly important. Current work mostly targets debugging semantic defects in ontologies.
Lambrix, Patrick, Liu, Qiang
core   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Alignment of ICNP® 2.0 Ontology and a proposed INCP® Brazilian Ontology

Revista Latino-Americana de Enfermagem, 2014
OBJECTIVE: to align the International Classification for Nursing Practice (ICNP®) Version 2.0 ontology and a proposed INCP® Brazilian Ontology.METHOD: document-based, exploratory and descriptive study, the empirical basis of which was provided by the ...
Carina Maris Gaspar Carvalho, Marcia Regina Cubas, Andreia Malucelli, Maria Miriam Lima da Nóbrega   +3 more
doaj   +1 more source

Review and Alignment of Domain-Level Ontologies for Materials Science

IEEE Access, 2023
The growing complexity and interdisciplinary nature of Materials Science research demand efficient data management and exchange through structured knowledge representation.
Anne De Baas, Pierluigi Del Nostro, Jesper Friis, Emanuele Ghedini, Gerhard Goldbeck, Ilaria Maria Paponetti, Andrea Pozzi, Arkopaul Sarkar, Lan Yang, Francesco Antonio Zaccarini, Daniele Toti   +10 more
doaj   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Matching biomedical ontologies through compact differential evolution algorithm

Systems Science & Control Engineering, 2019
Although biomedical ontologies have been widely used in the life science domain, the heterogeneous problem among biomedical ontologies hampers their inter-operability.
Xingsi Xue, Junfeng Chen
doaj   +1 more source

Comparison of ontology alignment systems across single matching task via the McNemar's test

, 2018
Ontology alignment is widely-used to find the correspondences between different ontologies in diverse fields.After discovering the alignments,several performance scores are available to evaluate them.The scores typically require the identified alignment ...
Atashin, Amir Ahooye, Hofman, Wout, Mohammadi, Majid, Tan, Yao-Hua   +3 more
core   +1 more source

LINC01116, a hypoxia‐lncRNA marker of pathological lymphangiogenesis and poor prognosis in lung adenocarcinoma

Molecular Oncology, EarlyView.
The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola, Rafael Lopes Goncalves, Marin Truchi, Caroline Lacoux, Célia Scribe, Hugo Cadis, Laetitia Guardini, Sophie Bekisz, Marius Ilié, Paul Hofman, Georges Vassaux, Bernard Mari, Roger Rezzonico   +12 more
wiley   +1 more source