Results 61 to 70 of about 1,038,617 (321)

Towards valid and reusable reference alignments — ten basic quality checks for ontology alignments and their application to three different reference data sets

open access: yesJournal of Biomedical Semantics, 2012
Identifying relationships between hitherto unrelated entities in different ontologies is the key task of ontology alignment. An alignment is either manually created by domain experts or automatically by an alignment system.
Beisswanger Elena, Hahn Udo
doaj   +1 more source

Ontology Matching with Knowledge Rules

open access: yes, 2015
Ontology matching is the process of automatically determining the semantic equivalences between the concepts of two ontologies. Most ontology matching algorithms are based on two types of strategies: terminology-based strategies, which align concepts ...
Dou, Dejing   +2 more
core   +1 more source

Algebras of Ontology Alignment Relations [PDF]

open access: yes, 2008
Correspondences in ontology alignments relate two ontology entities with a relation. Typical relations are equivalence or subsumption. However, different systems may need different kinds of relations. We propose to use the concepts of algebra of relations in order to express the relations between ontology entities in a general way. We show the benefits
openaire   +1 more source

ATF4‐mediated stress response as a therapeutic vulnerability in chordoma

open access: yesMolecular Oncology, EarlyView.
We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone   +11 more
wiley   +1 more source

Automated Annotation-Based Bio-Ontology Alignment with Structural Validation [PDF]

open access: yes, 2009
We outline the structure of an automated process to both align multiple bio-ontologies in terms of their genomic co-annotations, and then to measure the structural quality of that alignment.
Amanda White   +9 more
core   +2 more sources

User Validation in Ontology Alignment

open access: yes, 2016
User validation is one of the challenges facing the ontology alignment community, as there are limits to the quality of automated alignment algorithms. In this paper we present a broad study on user validation of ontology alignments that encompasses three distinct but interrelated aspects: the profile of the user, the services of the alignment system ...
Dragisic, Zlatan   +5 more
openaire   +3 more sources

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

Multimatcher Model to Enhance Ontology Matching Using Background Knowledge

open access: yesInformation, 2021
Ontology matching is a rapidly emerging topic crucial for semantic web effort, data integration, and interoperability. Semantic heterogeneity is one of the most challenging aspects of ontology matching.
Sohaib Al-Yadumi   +4 more
doaj   +1 more source

Ontological quality control in large-scale, applied ontology matching [PDF]

open access: yes, 2013
To date, large-scale applied ontology mapping has relied greatly on label matching and other relatively simple syntactic features. In search of more holistic and accurate alignment, we offer a suite of partially overlapping ontology mapping heuristics ...
Legg, Catherine, Sarjant, Samuel
core   +2 more sources

Data Linking with Ontology Alignment [PDF]

open access: yes, 2012
It is a trend to publish RDF data on the web, so that users can share information semantically. Then, linking isolated data sets together is highly needed. I would like to reduce the comparison scale by isolating the types of resources to be compared, so that it enhances the accuracy of the linking process.
openaire   +2 more sources

Home - About - Disclaimer - Privacy