Results 91 to 100 of about 1,450,496 (248)

Uncovering G Protein‐Coupled Receptors: Novel Targets and Biomarkers for Predicting Glioma Prognosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Low‐grade gliomas (LGG) exhibit significant heterogeneity and recurrence risk. G protein‐coupled receptors (GPCR) contribute to glioma malignant progression, but their prognostic value remains unclear. This work attempts to formulate a GPCR‐based outcome‐predicting model for LGG. Methods Based on TCGA LGG data, the enrichment scores
Jun Yang, Dongxu Zhang, Dongyuan Liu, Da Lin, Hao Wang   +4 more
wiley   +1 more source

Integrated PANoptosis Profiling Identifies Immunosuppressive Subtypes and a Prognostic Signature With Functional Validation of MLKL in Glioblastoma

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The prognosis of glioblastoma (GBM) remains highly unfavorable, largely due to high tumor heterogeneity and an immunosuppressive microenvironment. However, the functional role of PANoptosis in this context is poorly understood. Methods Patients were stratified via K‐means clustering. A risk score model was constructed using prognosis‐
Langfei Tian, Minghui Zhao, Yuanbo Hu, Kaiyue Wang, Haiguang Liu, Zetong Bai, Kebin Zheng   +6 more
wiley   +1 more source

Cerebrospinal Fluid Over Plasma Links Analytes to Cognitive Decline in Older Adults at Risk for Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To identify inflammatory analytes in cerebrospinal fluid (CSF) and plasma associated with cognitive decline in cognitively normal (CN) older adults at risk for Alzheimer's disease (AD). Methods In a longitudinal study of 118 CN older adults (65–80 years, 54% APOE ε4, 26% preclinical AD), 1331 CSF and 1501 plasma analytes were ...
Jagan A. Pillai, Audrey Zhu, Chunxuan Ma, Ming Wang, Yifan Yang, Lynn M. Bekris, Maria Khrestian, Frank P. DiFilippo, Mikhail Nasrallah, Aaron Burberry, James B. Leverenz, Yuan Hou, Feixiong Cheng, Stephen M. Rao   +13 more
wiley   +1 more source

NFDI MatWerk Ontology (MWO): A BFO‐Compliant Ontology for Research Data Management in Materials Science and Engineering

Advanced Engineering Materials, EarlyView.
This article presents the NFDI‐MatWerk Ontology (MWO), a Basic Formal Ontology‐based framework for interoperable research data management in materials science and engineering (MSE). Covering consortium structures, research data management resources, services, and instruments, MWO enables semantic integration, Findable, Accessible, Interoperable, and ...
Hossein Beygi Nasrabadi, Ebrahim Norouzi, Kostiantyn Hubaiev, Jörg Waitelonis, Harald Sack   +4 more
wiley   +1 more source

Reaching agreement over ontology alignments [PDF]

, 2006
When agents communicate, they do not necessarily use the same vocabulary or ontology. For them to interact successfully, they must find correspondences (mappings) between the terms used in their respective ontologies.
Terry Payne, Euzenat, Jerome, Payne, Terry R., Loredana Laera, Jérôme Euzenat, Tamma, Valentina, Valentina Tamma, Payne, Terry, Laera, Loredana, Bench-Capon, Trevor, Trevor Bench-capon   +10 more
core   +1 more source

Field Report from Collaborative Research Center 1625: Heterogeneous Research Data Management Using Ontology Representations

Advanced Engineering Materials, EarlyView.
A unified research data management framework for heterogeneous materials data is presented. The system integrates multimodal datasets using ontologies and knowledge graphs, enabling interoperability and FAIR (findable, accessible, interoperable, reusable) data principles. By linking data across scales and workflows, it supports reproducible, Artifitial
Doaa Mohamed, Samuel García Vázquez, Behnam Mardani, Victor Dudarev, Alfred Ludwig, Maribel Acosta, Markus Stricker   +6 more
wiley   +1 more source

Ontology Building of Manufacturing Quality Knowledge for Design Decision Support [PDF]

, 2010
This work was funded by National Natural Science Foundation of China (No: 70472066, 70771091), the project of Bureau of Science, Technology and Industry for National Defence, China (No. Z142008A001), the NPU Foundation for Humanities, Social Science, and
EYNARD, Benoit, ROUCOULES, Lionel, TONG, Shurong, MATTA, Nada, WANG, Keqin   +4 more
core  

An OWL-based ontology for semantic competency mapping and explainable assessment in digital STEM teacher professional development systems

Frontiers in Computer Science
The digital transformation of education has increased the need for interoperable and machine-interpretable frameworks that can support competency-based teacher professional development in STEM-oriented environments. This study proposes an ontology-driven
Karlygash Alibekkyzy, Madina Bazarova, Akmaral Sadakbayeva, Gulnaz Zhomartkyzy   +3 more
doaj   +1 more source

A Security Analysis Method of Security Protocol Implementation Based on Unpurified Security Protocol Trace and Security Protocol Implementation Ontology

IEEE Access, 2019
The security analysis of Security Protocol Implementations(SPI) is an important part of cybersecurity. However, with the strength of property protection and the widely used applications of code obfuscation technology, the previous security analysis ...
Xudong He, Jiabing Liu, Chin-Tser Huang, Dejun Wang, Bo Meng   +4 more
doaj   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source