Results 101 to 110 of about 269,978 (302)

Detecting and Correcting Conservativity Principle Violations in Ontology-to-Ontology Mappings [PDF]

open access: yes, 2014
In order to enable interoperability between ontology-based systems, ontology matching techniques have been proposed. However, when the generated mappings suffer from logical flaws, their usefulness may be diminished. In this paper we present an approximate method to detect and correct violations to the so-called conservativity principle where novel ...
SOLIMANDO, ALESSANDRO   +2 more
openaire   +5 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

Medical Systematized Nomenclature in Development Process of 11th Revision of International Classification of Diseases

open access: yesمدیریت اطلاعات سلامت, 2019
Today, with increase in the volume of machine-oriented medical data, the role of interoperability and integrity has become clear. The goal of this research was to investigate the methods of integrating of Systematized Nomenclature of Medicine-Clinical ...
Ali Sanaeifar   +2 more
doaj   +1 more source

Ontologies Change and Queries Break: Towards a Solution [PDF]

open access: yes, 2006
Keeping track of ontology changes is becoming a critical issue for ontology-based applications. Updating an ontology that is in use may result in inconsistencies between the ontology and the knowledge base, dependent ontologies and applications/services.
Alani, Harith   +2 more
core  

Managing contextual information in semantically-driven temporal information systems [PDF]

open access: yes, 2011
Context-aware (CA) systems have demonstrated the provision of a robust solution for personalized information delivery in the current content-rich and dynamic information age we live in.
Isiaq, SO, Osman, T, Peytchev, E
core   +1 more source

A Cooperative Approach for Composite Ontology Mapping [PDF]

open access: yes, 2008
This paper proposes a cooperative approach for composite ontology mapping. We first present an extended classification of automated ontology matching and propose an automatic composite solution for the matching problem based on cooperation. In our proposal, agents apply individual mapping algorithms and cooperate in order to change their individual ...
Trojahn, Cássia   +3 more
openaire   +2 more sources

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

open access: yesFEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu   +10 more
wiley   +1 more source

Grounding semantic web services with rules [PDF]

open access: yes, 2008
Semantic web services achieve effects in the world through web services, so the connection to those services - the grounding - is of paramount importance.
Domingue, John, Lambert, David
core   +2 more sources

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

open access: yesFEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Towards Ontology Mapping: DL View or Graph View?

open access: yes, 2006
Ontology is important in sharing and reusing knowledge. It also plays a crucial role in the development of Semantic Web. The paper discusses the DL(Description Logic) and graph view on ontology. Different perspectives have different models and approaches
Huang, Yongjian, Shadbolt, Nigel
core  

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