Results 11 to 20 of about 265,248 (262)
Obesity Induces Ovarian Inflammation and Reduces Oocyte Quality.
Reproduction, 2019 In the US, 36.5 percent of women between the ages of 20-39 are obese. This obesity results in not only metabolic disorders including type II diabetes and cardiovascular disease, but also impaired female fertility.
A. Snider, J. Wood
semanticscholar +1 more source
Impact of Maternal Age on Oocyte and Embryo Competence
Frontiers in Endocrinology, 2018 The overall success of human reproduction, either spontaneously or after IVF, is highly dependent upon maternal age. The main reasons for age-related infertility include reduced ovarian reserve and decreased oocyte/embryo competence due to aging insults,
D. Cimadomo +5 more
semanticscholar +1 more source
Human Reproduction Update, 2016 BACKGROUND Successful cryopreservation of oocytes and embryos is essential not only to maximize the safety and efficacy of ovarian stimulation cycles in an IVF treatment, but also to enable fertility preservation.
L. Rienzi +7 more
semanticscholar +1 more source
Impact of Oxidative Stress on Age-Associated Decline in Oocyte Developmental Competence
Frontiers in Endocrinology, 2019 Reproductive capacity in women starts to decline beyond their mid-30s and pregnancies in older women result in higher rates of miscarriage with aneuploidy.
Hiroyuki Sasaki +7 more
semanticscholar +1 more source
Aspects of follicular and oocyte maturation that affect the developmental potential of embryos.
Journal of reproduction and fertility. Supplement, 2019 The ability to mature, be fertilized and finally to develop into a viable embryo is acquired gradually by the oocyte during progressive differentiation throughout folliculogenesis.
P. Mermillod, B. Oussaid, Y. Cognié
semanticscholar +1 more source
The art of oocyte meiotic arrest regulation
Reproductive Biology and Endocrinology, 2019 A central dogma of mammalian reproductive biology is that the size of the primordial follicle pool represents reproductive capacity in females. The assembly of the primordial follicle starts after the primordial germ cells (PGCs)-derived oocyte releases ...
Bo Pan, Julang Li
semanticscholar +1 more source
Integrated Environmental Assessment and Management, EarlyView., 2023 Abstract In the Lake Koocanusa‐Kootenai River system (Montana, USA and British Columbia, Canada), selenium (Se) contamination has become an international concern and is suspected to contribute to the observed burbot (Lota lota) population collapse. Due to our limited ability to sample burbot in Lake Koocanusa for monitoring studies, we used a reference
Stephanie D. Graves +6 more
wiley +1 more source
International Journal of Molecular Sciences, 2019 Mammalian oocytes and early embryos derived from in vitro production are highly susceptible to a variety of cellular stresses. During oocyte maturation and preimplantation embryo development, functional proteins must be folded properly in the endoplasmic
T.-A. Lin +5 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley +1 more source
Molecular Oncology, EarlyView.This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti +10 more
wiley +1 more source