Results 71 to 80 of about 269,488 (343)

Oocyte maturation: gamete-somatic cells interactions, meiotic resumption, cytoskeletal dynamics and cytoplasmic reorganization.

Human Reproduction Update, 2015
BACKGROUND In a growth phase occurring during most of folliculogenesis, the oocyte produces and accumulates molecules and organelles that are fundamental for the development of the preimplantation embryo.
G. Coticchio, M. Dal Canto, M. Mignini Renzini, M. Guglielmo, F. Brambillasca, D. Turchi, P. Novara, R. Fadini   +7 more
semanticscholar   +1 more source

Gentle Label‐Free Nonlinear Optical Imaging Relaxes Linear‐Absorption‐Mediated Triplet

Advanced Science, EarlyView.
The phototoxicity in nonlinear optical microscopy arises mainly from linear absorption of intrinsic biomolecules rather than nonlinear absorption. This mechanism is supported by a reproducible phototoxicity assay based on widely available chicken breast.
Geng Wang, Lianhuang Li, Janet E. Sorrells, Jianxin Chen, Haohua Tu   +4 more
wiley   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Mitochondria Synthesize Melatonin to Ameliorate Its Function and Improve Mice Oocyte’s Quality under in Vitro Conditions

International Journal of Molecular Sciences, 2016
The physiology of oocyte in vitro maturation remains elusive. Generally, the oocytes have a very low maturation rate under in vitro conditions. In the current study, we found that melatonin promotes the maturation of oocytes in which mitochondria play a ...
Changjiu He, Jing Wang, Zhenzhen Zhang, Minghui Yang, Yu Li, X. Tian, Teng Ma, Jingli Tao, Kuanfeng Zhu, Yukun Song, Pengyun Ji, Guoshi Liu   +11 more
semanticscholar   +1 more source

Restoration of SIRT3 Expression in Aged Mice Alleviates UUO‐Induced Renal Fibrosis by Reducing GSK‐3β Hyperacetylation

Advanced Science, EarlyView.
SIRT3 expression is significantly downregulated in the aged kidney, rendering the kidney more vulnerable to fibrotic changes in obstructive nephropathy. By promoting GSK‐3β deacetylation, SIRT3 indirectly inhibits Wnt/β‐catenin signaling, thereby suppressing renal fibrosis.
Jing Wang, Xiang Ren, Huan Lu, Zihao Guo, Xing Li, Yiqun Tian, Yisheng Yin, Zhenliang Qin, Kun Yun, Minglong Wu, Gang Chen, Xiaoyong Zeng   +11 more
wiley   +1 more source

SET Improved Oocyte Maturation by PP2A and Inhibited Oocyte Apoptosis in Mouse Oocytes

, 2021
Abstract Background: SET is a multifunctional protein involved in a variety of molecular processes such as transcription control, chromatin remodeling, cell apoptosis, and cell-cycle regulation. In ovaries SET is predominantly expressed in theca cells and oocytes. And in PCOS patients the expression of SET was increased than normal people.
Lingling Gao, Siying Wang, Jianbo Xu, Dan Lu, Yugui Cui   +4 more
openaire   +2 more sources

Human oocyte developmental potential is predicted by mechanical properties within hours after fertilization

Nature Communications, 2016
The causes of embryonic arrest during pre-implantation development are poorly understood. Attempts to correlate patterns of oocyte gene expression with successful embryo development have been hampered by the lack of reliable and nondestructive predictors
Livia Z. Yanez, Jinnuo Han, B. Behr, R. R. Pera, David B. Camarillo   +4 more
semanticscholar   +1 more source

Tracing and Capturing the Epiblast Pluripotency of Sheep Preimplantation Embryos

Advanced Science, EarlyView.
This study performs a comprehensive single‐cell transcriptome analysis of sheep embryos from embryonic (E) day 1 to E14 to elucidate the mechanism of early lineage specification and the pluripotency changes (naïve, formative, and primed) of epiblast.
Jinying Zhang, Runbo Li, Ruijie Luo, Qiang Zhang, Zimo Zhao, Haishen Xu, Minglei Zhi, Wenjie Jiang, Meng Wang, Xinze Chen, Zhiqiang Feng, Yingjie Wang, Yuhan Yang, Pengcheng He, Hanyue Su, Tianzhi Chen, Shunxin Wang, Yixuan Yao, Jinghui Yang, Fan Zhao, Tingting Li, Haitao Wang, Xiaosheng Zhang, Jinlong Zhang, Qiuyue Liu, Shuai Gao, Yuchang Yao, Jianyong Han, Suying Cao   +28 more
wiley   +1 more source

Coenzyme Q10 restores oocyte mitochondrial function and fertility during reproductive aging

Aging Cell, 2015
Female reproductive capacity declines dramatically in the fourth decade of life as a result of an age‐related decrease in oocyte quality and quantity.
A. Ben-Meir, E. Burstein, A. Borrego-Alvarez, J. Chong, E. Wong, T. Yavorska, T. Naranian, M. Chi, Ying Wang, Yaakov Bentov, Jennifer Alexis, J. Meriano, H. Sung, D. Gasser, K. Moley, S. Hekimi, R. Casper, A. Jurisicova   +17 more
semanticscholar   +1 more source

RSPO2 Coordinates with GDF9:BMP15 Heterodimers to Promote Granulosa Cell and Oocyte Development in Mice

Advanced Science, EarlyView.
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang, Hongjiang Li, Liji You, Shuhui Wang, Jinglei Bie, Ziyang Su, Lanying Shi, You‐Qiang Su   +7 more
wiley   +1 more source