Results 131 to 140 of about 1,544,426 (289)

Single Ca2+ transients vs oscillatory Ca2+ signaling for assisted oocyte activation : limitations and benefits

open access: yes, 2018
Oocyte activation is a calcium (Ca2+)-dependent process that has been investigated in depth, in particular, regarding its impact on assisted reproduction technology (ART).
Björn Heindryckx   +9 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

open access: yesMedicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli   +5 more
wiley   +1 more source

Early rescue oocyte activation at 5 h post-ICSI is a useful strategy for avoiding unexpected fertilization failure and low fertilization in ICSI cycles. [PDF]

open access: yesFront Endocrinol (Lausanne), 2023
Xue L   +12 more
europepmc   +1 more source

Case series: Kikuchi‐Fujimoto disease with diagnostic overlap

open access: yesRheumatology &Autoimmunity, EarlyView.
Kikuchi‐Fujimoto disease (KFD) is a rare, self‐limiting necrotizing lymphadenitis that poses significant diagnostic challenges due to its overlap with tuberculosis, systemic lupus erythematosus (SLE), and malignancy. We present four cases highlighting distinct diagnostic complexities: KFD mimicking tuberculosis with concomitant latent TB infection and ...
Ecem Kalemoglu   +6 more
wiley   +1 more source

Oocyte-dependent activation of MTOR in cumulus cells controls the development and survival of cumulus-oocyte complexes.

open access: yes, 2016
Communication between oocytes and their companion somatic cells promotes the healthy development of ovarian follicles, which is crucial for producing oocytes that can be fertilized and are competent to support embryogenesis.
Su, You-Qiang   +11 more
core   +1 more source

Impact of sleep insufficiency and recovery on cancer development

open access: yesSleep Research, EarlyView.
Abstract Sleep plays a critical role in overall health, and modern lifestyles, such as shift work and late‐night activities, can significantly impact sleep condition. Insufficient sleep has been associated with various adverse health outcomes, including an increased risk of tumor development.
Xiaxi Li, Chuanyuan Li, Yi Zhang
wiley   +1 more source

Corrigendum: A novel assisted oocyte activation method improves fertilization in patients with recurrent fertilization failure. [PDF]

open access: yesFront Cell Dev Biol, 2023
Wang M   +10 more
europepmc   +1 more source

Purification of Bovine Sperm Membrane-Proteins Involved in Sperm-Oocyte Interactions: Adhesion, Fusion, and Activation

open access: yes, 2007
At fertilization interactions between sperm and oocyte proteins are pivotal to oocyte activation, fusion and embryo development.The proteins involved in bovine activation have not yet been isolated, identified or characterized.
Kenneth Aston   +13 more
core   +1 more source

Assessment of Oxidative Stress, Vitellogenin, and Human Health Risks Derived From Nile Tilapia Exposed to Metals and Metalloids in Southeastern Brazil

open access: yesEnvironmental Toxicology, EarlyView.
ABSTRACT Urban coastal lagoons are highly vulnerable ecosystems increasingly affected by metal contamination, as well as multiple anthropogenic stressors. This study evaluated ecotoxicological and human health risks associated with chronic metal exposure in Nile tilapia (Oreochromis niloticus) from an anthropogenically impacted lagoon in southeastern ...
Julia Araújo Alves   +8 more
wiley   +1 more source

Endometriosis disrupts oocyte metabolism and cortical granule function, impairing fertilization

open access: yesReproductive Biology and Endocrinology
Background Endometriosis is a chronic inflammatory disease strongly associated with reduced oocyte quality and subfertility, yet the underlying cytoplasmic defects remain poorly understood.
Omar G. Klinsky   +4 more
doaj   +1 more source

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