Results 101 to 110 of about 15,361,986 (325)

Vitamins, Coenzyme Q10, and Antioxidant Strategies to Improve Oocyte Quality in Women with Gynecological Cancers: A Comprehensive Review

open access: yesAntioxidants
Background: Gynecological cancers, including ovarian, cervical, and endometrial cancers, significantly affect both survival and reproductive health in women.
Isaic Alexandru   +7 more
doaj   +1 more source

Association of exosomal microRNAs in human ovarian follicular fluid with oocyte quality.

open access: yesBiochemical and Biophysical Research Communications - BBRC, 2020
The postponement of childbearing by women has led to an increase in infertility. The reproductive aging process leads to a decrease in both the quantity and quality of oocytes.
Di Zhang   +7 more
semanticscholar   +1 more source

Oocyte donation pregnancies-non-disclosure of oocyte recipient status to obstetric care providers and perinatal outcomes [PDF]

open access: yes, 2018
Background: Oocyte donation pregnancies-non-disclosure of oocyte recipient (OR) status to obstetric care providers and perinatal outcomes. Many studies report a higher rate of pregnancy-induced hypertension (PIH) and severe pre-eclampsia (PET) in OR ...
O'Donoghue, Keelin   +3 more
core   +1 more source

2014 Texas Integrated Report Index of Water Quality Impairments [PDF]

open access: yes, 2015
This technical report briefly describes the location and type of water quality concerns in Waller Creek.Waller Creek Working ...
Texas Commission on Environmental Quality
core   +1 more source

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

open access: yesAdvanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang   +6 more
wiley   +1 more source

Maternal Exercise Rescues Embryonic Osteogenesis Impaired due to POLG Mutation Through a Potential Apelin‐ATF4 Axis

open access: yesAdvanced Science, EarlyView.
Maternal exercise (ME) increases apelin abundance across maternal and fetal tissues and is associated with improved fetal osteogenesis under POLG mutation‐induced mitochondrial dysfunction. Apelin‐APJ signaling is linked to enhanced mitochondrial function, Akt phosphorylation, and ATF4‐RUNX2 association, supporting coordinated fetal bone remodeling ...
Song Ah Chae   +5 more
wiley   +1 more source

Sirt1 sustains female fertility by slowing age‐related decline in oocyte quality required for post‐fertilization embryo development

open access: yesAging Cell, 2020
The NAD+‐dependent sirtuin deacetylase, Sirt1, regulates key transcription factors strongly implicated in ageing and lifespan. Due to potential confounding effects secondary to loss of Sirt1 function from the soma in existing whole‐animal mutants, the in
J. D. Iljas, Zhe Wei, H. Homer
semanticscholar   +1 more source

Aberrant cortex contractions impact mammalian oocyte quality

open access: yes
The cortex controls cell shape. In mouse oocytes, the cortex thickens in an Arp2/3-complex-dependent manner, ensuring chromosome positioning and segregation.
Verlhac, Marie-Hélène   +12 more
core   +3 more sources

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

High coverage of targeted lipidomics revealed lipid changes in the follicular fluid of patients with insulin-resistant polycystic ovary syndrome and a positive correlation between plasmalogens and oocyte quality

open access: yesFrontiers in Endocrinology
BackgroundPolycystic ovary syndrome with insulin resistance (PCOS-IR) is the most common endocrine and metabolic disease in women of reproductive age, and low fertility in PCOS patients may be associated with oocyte quality; however, the molecular ...
Meizi Zhang   +11 more
doaj   +1 more source

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