Results 91 to 100 of about 15,361,986 (325)

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Chenodeoxycholic acid improves oocyte maturation and embryo quality during bisphenol A exposure by activating the EGFR-ERK1/2 signaling pathway

Ecotoxicology and Environmental Safety
Chenodeoxycholic acid (CDCA) is a free bile acid present in the follicular fluid surrounding growing oocytes. In this study, we demonstrate that supplementation with CDCA activates the EGFR signaling in cumulus-oocyte complexes (COCs) to improve oocyte ...
Zhi-Yong An, Tuo Zhang, Gao-Jie Lu, Xiaoyufan Xu, Xue Fang, Sheng-Zhong Han, Shuang-Yan Chang, Xi-Jun Yin, Lin-Hu Quan, Jin-Dan Kang   +9 more
doaj   +1 more source

Growth hormone alleviates oxidative stress and improves oocyte quality in Chinese women with polycystic ovary syndrome: a randomized controlled trial

Scientific Reports, 2020
Oxidative stress (OS) is associated with poor oocyte quality and in vitro fertilization and embryo transfer (IVF-ET) outcomes for patients with polycystic ovary syndrome (PCOS).
Yan Gong, Sha Luo, P. Fan, Song Jin, Hui-Li Zhu, Tang Deng, Yi Quan, Wei Huang   +7 more
semanticscholar   +1 more source

Spatially Organized Human Ovarian Spheroids Instruct Endometrial Morphogenesis

Advanced Science, EarlyView.
A spatially organized human follicle‐like spheroid (SPHEGaT) composed of granulosa cells (GCs) and stromal‐derived theca‐like cells (TLCs) establishes sustained steroidogenesis in vitro. When co‐cultured with human endometrial organoids (EMOs), estradiol (E2) and progesterone (P4) exchange induces secretory/progesterone‐responsive differentiation ...
Maria João Sousa, Silke De Vriendt, Lixian Liu, Thalles Fernando Rocha Ruiz, Hugo Vankelecom, Christiani Andrade Amorim   +5 more
wiley   +1 more source

The efficacy of melatonin administration on oocyte quality

Gynecological Endocrinology, 2011
The aim of the study was to evaluate the efficacy of melatonin administration on oocyte quality in women underwent in vitro fertilization (IVF) cycles. Eighty-five women undergoing IVF cycles were randomized in two groups during IVF-embryo transfer (ET) procedure, 40 women with melatonin treatment (A) and 45 women without melatonin treatment (B ...
A Sertaç, Batıoğlu, Uğraş, Sahin, Beril, Gürlek, Nazire, Oztürk, Evrim, Unsal   +4 more
openaire   +2 more sources

Deciphering Anti‐Cancer Drug Efficacy Through Nanomechanical Vibrations in Living Gastric Cancer Organoids

Advanced Science, EarlyView.
This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang, Qiubo Chen, Shihai Lan, Liang Zhu, Shuaiyu Liu, Yan Xia, Yalu Zhang, Hanhui Yao, Yongman Liu, Shangquan Wu, Qingchuan Zhang   +10 more
wiley   +1 more source

Ovarian ageing and the impact on female fertility [version 1; referees: 2 approved]

F1000Research, 2018
Female fertility decreases with increasing age, a reflection of declining oocyte quantity and quality. The menopausal transition occurs when the oocyte quantity falls below a threshold level.
Beverley Vollenhoven, Sarah Hunt
doaj   +1 more source

An Eight Year Experience of Autologous Oocyte Vitrification for Infertile Patients Owing to Unavailability of Sperm on Oocyte Retrieval Day

Frontiers in Medicine, 2021
Objective: The objective of this study was to provide a descriptive analysis of the clinical outcomes achieved in oocyte vitrification in cases where sperm was unavailable on oocyte retrieval day, and to identify predictors of oocyte survival.Methods ...
Xiao Fu, Xiao Fu, Xiao Fu, Xiaojie Liu, Xiaojie Liu, Xiaojie Liu, Jing Li, Jing Li, Jing Li, Meng Zhang, Meng Zhang, Meng Zhang, Jingjing Jiang, Jingjing Jiang, Qianqian Chen, Qianqian Chen, Mei Li, Mei Li, Shanshan Gao, Shanshan Gao, Shanshan Gao, Jinlong Ma, Jinlong Ma   +22 more
doaj   +1 more source

Oocyte Donation [PDF]

, 2017
The use of donor oocytes has expanded the scope of assisted reproductive technology (ART) for women with poor oocyte quantity and quality. In vitro fertilisation with oocyte donation (IVF-OD) is considered to give better implantation, pregnancy, and ...
Nalini Mahajan
core  

The role of declining ataxia-telangiectasia-mutated (ATM) function in oocyte aging

Cell Death Discovery
Despite the advances in the understanding of reproductive physiology, the mechanisms underlying ovarian aging are still not deciphered. Recent research found an association between impaired ATM-mediated DNA double-strand break (DSB) repair mechanisms and
Reiko Suzuki, Xiujuan Tan, Katarzyna J. Szymanska, Nada Kubikova, Columba Avila Perez, Dagan Wells, Kutluk H. Oktay   +6 more
doaj   +1 more source