Results 71 to 80 of about 15,361,986 (325)

Ovarian aging: energy metabolism of oocytes

Journal of Ovarian Research
In women who are getting older, the quantity and quality of their follicles or oocytes and decline. This is characterized by decreased ovarian reserve function (DOR), fewer remaining oocytes, and lower quality oocytes.
Shenglan Bao, Tailang Yin, Su Liu
doaj   +1 more source

Mitochondrial enrichment in infertile patients: a review of different mitochondrial replacement therapies

Therapeutic Advances in Reproductive Health, 2021
Poor ovarian responders exhibit a quantitative reduction in their follicular pool, and most cases are also associated with poor oocyte quality due to patient’s age, which leads to impaired in vitro fertilisation outcomes.
Cristina Rodríguez-Varela, Sonia Herraiz, Elena Labarta   +2 more
doaj   +1 more source

Perspectives, experiences, and choices of parents of children conceived following oocyte donation [PDF]

, 2013
This paper reports on and discusses the findings of an online survey initiated by the Donor Sibling Registry of 108 parents of children conceived following oocyte donation. Respondents generally supported early disclosure of donor conception to the child,
Kramer, Wendy, Schneider, Jennifer, Blyth, Eric   +2 more
core   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Effect of estrous cycle stage on oocyte in vitro maturation of domestic cats reared under tropical conditions

Revista Científica, 2023
Oocyte maturation is a critical step for in vitro embryo production. In female cats, findings on the influence of the estrous cycle stage on oocyte quality and maturation are contradictory.
Enmar Monasterio–Alemán, Luis Monasterio–Oquendo, Liset Zambrano–Vivas, Verónica Arboleda–Caldera, Carla Osorio–Melendez, José Aranguren–Méndez, Fernando Perea–Ganchou, Hugo Hernández–Fonseca   +7 more
doaj   +1 more source

Iron accumulation in ovarian microenvironment damages the local redox balance and oocyte quality in aging mice

Redox Biology
Accumulating oxidative damage is a primary driver of ovarian reserve decline along with aging. However, the mechanism behind the imbalance in reactive oxygen species (ROS) is not yet fully understood.
Ye Chen, Jiaqi Zhang, Ying Tian, Xiang-Ning Xu, Bi-Cheng Wang, Ziqi Huang, Shuo Lou, Jingyi Kang, Ningning Zhang, Jing Weng, Yuanjing Liang, Wei Ma   +11 more
semanticscholar   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

The effect of maturation and aging on the quality of mammalian oocytes

Czech Journal of Animal Science
The aim of this review was to summarise current knowledge regarding the effects of maturation, activation and aging on oocyte quality. Two main forms of aging were distinguished: (i) postovulatory aging, which occurs after ovulation due to a prolonged ...
Andrea Nesvadbova, Jiri Bezdicek, Alexander Makarevich, Ludek Stadnik   +3 more
doaj   +1 more source

Polyethylene microplastic exposure adversely affects oocyte quality in human and mouse.

Environment International
Microplastics (MPs) are pervasive environmental contaminants, resulting in unavoidable human exposure. This study identified MPs in follicular fluid and investigated the specific MPs and mechanisms that adversely affect oocytes.
Qiao-Ling Wang, Feng-Li Chi, Ying-Dong Liu, Qiurong Chang, Siyu Chen, Pengcheng Kong, Wan-Li Yang, Wen-Qiang Liu, Xiaoming Teng, Yan Zhao, Yi Guo   +10 more
semanticscholar   +1 more source

Advanced maternal age alters expression of maternal effect genes that are essential for human oocyte quality

Aging, 2020
To investigate the effects of maternal age on the quality of oocytes, we used single-cell RNA sequencing to detect global gene transcriptome and identify key genes affected by advanced age in human mature oocytes.
Jingjing Zhang, Xiao-Yan Liu, L. Chen, Shouxin Zhang, Xia Zhang, C. Hao, Yi-Liang Miao   +6 more
semanticscholar   +1 more source