Results 61 to 70 of about 87,639 (309)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Updating the markers for oocyte quality evaluation: intracellular temperature as a new index

Reproductive Medicine and Biology, 2018
Background The developmental competence of an embryo is principally dictated by the oocyte. Usually, oocyte selection is based on morphological properties; however, all morphological criteria that are currently used for the grading and screening of ...
Yumi Hoshino
doaj   +1 more source

Fumonisin B1 exposure deteriorates oocyte quality by inducing organelle dysfunction and DNA damage in mice

Ecotoxicology and Environmental Safety, 2021
Oocyte quality is critical for fertilization and early embryo development. Fumonisin B1 (FB1) is a Fusarium mycotoxin and it is commonly found in contaminated food and feedstuff, posing a potential health hazard to both animals and human. FB1 is reported
Yue Wang, Yao Xu, Jia-Qian Ju, Jing-Cai Liu, Shao-Chen Sun   +4 more
doaj   +1 more source

M-phase promoting factor (MPF) and mitogen activated protein kinases (MAPK) activities of domestic cat oocytes matured in vitro and in vivo [PDF]

, 2004
This work was undertaken in order to examine M-phase promoting factor (MPF) and mitogen-activated protein kinases (MAPK) activities during meiotic progression of cat oocytes cultured in two different media for two different incubation times and ...
Bogliolo, Luisa, Bonelli, Piero, Ledda, Sergio, Leoni, Giovanni Giuseppe, Madau, Laura, Naitana, Salvatore, Pau, Salvatore, Santucciu, Cinzia, Zedda, Maria Teresa   +8 more
core  

Building a Framework for Sexual and Reproductive Health Care in the Rheumatology Context: Content and Approaches

Arthritis Care &Research, EarlyView.
People with systemic autoimmune and rheumatic diseases (SARDs) are at higher risk than the general population of experiencing adverse pregnancy and perinatal outcomes such as preeclampsia, intrauterine growth restriction, and maternal and/or fetal death.
Mehret Birru Talabi, Sonya Borrero
wiley   +1 more source

Chenodeoxycholic acid improves oocyte maturation and embryo quality during bisphenol A exposure by activating the EGFR-ERK1/2 signaling pathway

Ecotoxicology and Environmental Safety
Chenodeoxycholic acid (CDCA) is a free bile acid present in the follicular fluid surrounding growing oocytes. In this study, we demonstrate that supplementation with CDCA activates the EGFR signaling in cumulus-oocyte complexes (COCs) to improve oocyte ...
Zhi-Yong An, Tuo Zhang, Gao-Jie Lu, Xiaoyufan Xu, Xue Fang, Sheng-Zhong Han, Shuang-Yan Chang, Xi-Jun Yin, Lin-Hu Quan, Jin-Dan Kang   +9 more
doaj   +1 more source

Comparison of PUFA profiles in the blood and in follicular fluid and its association with follicular dynamics after PGF2α induced luteolysis in dairy cows [PDF]

, 2016
The objectives of the present study were to examine the fatty acid (FA) profiles in serum and in the follicular fluid (FF) and the association between polyunsaturated fatty acid level (PUFA) and follicular growth dynamics following induced luteolysis in ...
Adamov, Nikola, Atanasov, Branko, Davkov, Filip, Dovenski, Toni, Hajrulai-Musliu, Zehra, Hostens, Miel, Opsomer, Geert, Uzunov, Risto, Velev, Romel   +8 more
core   +3 more sources

The effects of vitrification on oocyte quality

Biology of Reproduction, 2021
Abstract Vitrification, is an ultra-rapid, manual cooling process that produces glass-like (ice crystal-free) solidification. Water is prevented from forming intercellular and intracellular ice crystals during cooling as a result of oocyte dehydration and the use of highly concentrated cryoprotectant.
Ching-Chien, Chang, Daniel B, Shapiro, Zsolt Peter, Nagy   +2 more
openaire   +2 more sources

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

Advanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi, David J. Sharkey, Nicole O. McPherson, Markos Negash Alemie, Krasimir Vasilev, Sarah A. Robertson   +5 more
wiley   +1 more source

Ovarian ageing and the impact on female fertility [version 1; referees: 2 approved]

F1000Research, 2018
Female fertility decreases with increasing age, a reflection of declining oocyte quantity and quality. The menopausal transition occurs when the oocyte quantity falls below a threshold level.
Beverley Vollenhoven, Sarah Hunt
doaj   +1 more source