Results 51 to 60 of about 87,639 (309)

Mitochondrial enrichment in infertile patients: a review of different mitochondrial replacement therapies

Therapeutic Advances in Reproductive Health, 2021
Poor ovarian responders exhibit a quantitative reduction in their follicular pool, and most cases are also associated with poor oocyte quality due to patient’s age, which leads to impaired in vitro fertilisation outcomes.
Cristina Rodríguez-Varela, Sonia Herraiz, Elena Labarta   +2 more
doaj   +1 more source

Effect of estrous cycle stage on oocyte in vitro maturation of domestic cats reared under tropical conditions

Revista Científica, 2023
Oocyte maturation is a critical step for in vitro embryo production. In female cats, findings on the influence of the estrous cycle stage on oocyte quality and maturation are contradictory.
Enmar Monasterio–Alemán, Luis Monasterio–Oquendo, Liset Zambrano–Vivas, Verónica Arboleda–Caldera, Carla Osorio–Melendez, José Aranguren–Méndez, Fernando Perea–Ganchou, Hugo Hernández–Fonseca   +7 more
doaj   +1 more source

Oocyte maturation in the toad Rhinella arenarum (Amphibia, Anura): Evidence of cAMP involvement in steroid production and action [PDF]

, 2018
In this work, we describe the participation of the adenylate cyclase/3′-5′-cyclic adenonsine monophosphate (cAMP) pathway in the seasonal follicular secretion of progesterone (P 4 ) and testosterone (T), and its relationship with the maturation of ...
Arias Torres, Arias Torres, Canosa, Cerdá, Das, Deng, Eyers, Ferrell, Fortune, Gohin, Gohin, Hammes, Higashijima, Jalabert, Kamangar, Khan, Kwon, Kwon, Levin, Lin, Lin, Lubzens, Marteil, Medina, Miedlich, Nader, Nagahama, Norris, O'Brien, Pang, Pickford, Rasar, Romo, Sadler, Schuetz, Sen, Sen, Smith, Sánchez Toranzo, Sánchez Toranzo, Thomas, Voronina, Vu, White, Yamamoto, Yang, Zelarayán, Zelarayán, Zelarayán   +48 more
core   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Ovarian aging: energy metabolism of oocytes

Journal of Ovarian Research
In women who are getting older, the quantity and quality of their follicles or oocytes and decline. This is characterized by decreased ovarian reserve function (DOR), fewer remaining oocytes, and lower quality oocytes.
Shenglan Bao, Tailang Yin, Su Liu
doaj   +1 more source

The consequences of nuclear transfer for mammalian foetal development and offspring survival : a mitochondrial DNA perspective [PDF]

, 2004
Review of the articleThe introduction of nuclear transfer (NT) and other technologies that involve embryo reconstruction require us to reinvestigate patterns of mitochondrial DNA (mtDNA) transmission, transcription and replication.
Anderson, Barrientos, Barrientos, Barritt, Barritt, Birky, Birky, Blok, Boiani, Bortvin, Boulet, Brenner, Campbell, Cibelli, Clark, Clayton, Cohen, Cormier, Cummins, Davis, Do, Dunbar, Evans, Fisher, Gaertig, Gahan, Giles, Goto, Gyllensten, Hauswirth, Hayakawa, Hiendleder, Hoeh, Holt, Howell, Hsieh, Huo, Inoue, Jansen, Jenuth, Kaneda, Kaukonen, King, King, Laipis, Larsson, Larsson, Lazzari, Magnusson, Maher, Mandel, Marchington, Michaels, Moraes, Moyes, Pik  , Poulton, Poulton, Reik, Reynier, Saada, Schon, Schutz, Schwartz, Shi, Shitara, Shoffner, Smith, St. John, Steinborn, Steinborn, Sutovsky, Takeda, Takeda, Torroni, Van Blerkom, Van Blerkom, Van Goethem, Wakayama, Wallace, Zhang   +80 more
core   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

Comparison of ovarian cycles of Hungarian riverine fish species representing different spawning strategies [PDF]

, 2008
Investigations on the ovarian cycle of fish species that inhabit Hungarian rivers are necessitated by both environmental and economic reasons. The objective of our research was to explore new fundamental knowledge concerning the ovarian cycle of the ...
Baska, Ferenc, Gál, János, Hegyi, Árpád, Horváth, Ákos, Lefler, Kinga Katalin, Szabó, Tamás, Urbányi, Béla   +6 more
core   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

An increase of phosphatidylcholines in follicular fluid implies attenuation of embryo quality on day 3 post-fertilization

BMC Biology, 2021
Background Although oocyte quality is the dominant factor determining embryo quality, few studies have been conducted to evaluate embryo quality based on the metabolites related to the oocyte. With quantification of the follicular fluid (FF) metabolites,
Ju Wang, Wei Zheng, Shuoping Zhang, Keqiang Yan, Miao Jin, Huiling Hu, Zhen Ma, Fei Gong, Guangxiu Lu, Yan Ren, Liang Lin, Ge Lin, Liang Hu, Siqi Liu   +13 more
doaj   +1 more source