Results 111 to 120 of about 15,361,986 (325)

An Injectable ROS‐Responsive Nanozyme Hydrogel Regulates the Uterine Microenvironment to Prevent Intrauterine Adhesions

open access: yesAdvanced Science, EarlyView.
The injectable CeTA@GPP hydrogel is administered via intrauterine injection, forming a protective barrier. In the high ROS inflammatory microenvironment of injured endometrium, boronate ester cleavage triggers responsive CeTA release and local enrichment.
Peixian Cheng   +8 more
wiley   +1 more source

Factors affecting oocyte quality in New Zealand dairy cows

open access: yes, 2023
 Oocyte quality is an important factor affecting the reproductive  performance of dairy cows. Good oocyte quality is essential for  embryonic survival through early pregnancy as maternal transcripts,  cellular machinery, and regulatory factors required ...
Charlotte Reed (8514417)
core   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Excessive lipid contents in immature oocytes from repeat breeder dairy heifers [PDF]

open access: yes, 2011
The repeat breeding problem in cattle is widespread among all the heavy dairy breeds in cattle and is being considered as a major problem throughout the world. The aetiology of the repeat breeding is of various origins.
Awasthi, Hitesh
core   +1 more source

Biosynthesis and expression of zona pellucida glycoproteins in mammals [PDF]

open access: yes, 2001
The zona pellucida (ZP) is an extracellular matrix surrounding the oocyte and the early embryo that exerts several important functions during fertilization and early embryonic development.
Töpfer-Petersen, E.   +2 more
core   +1 more source

Antigen‐Detected NMR for Minimal Epitope Engineering and Structure‐Guided Selection of a NaV1.7‐Selective Nanobody

open access: yesAdvanced Science, EarlyView.
A minimal extracellular epitope from voltage‐gated sodium channel NaV1.7 was engineered into an isotope‐labelled antigen for antigen‐detected nuclear magnetic resonance (NMR). Together with AlphaFold2 (AF2), this enabled structure‐guided selection of R4C8, a human NaV1.7‐selective nanobody that labels fixed NaV1.7‐expressing cells and produces staining
Junyu Liu   +27 more
wiley   +1 more source

Obesity Induces Ovarian Inflammation and Reduces Oocyte Quality.

open access: yesReproduction, 2019
In the US, 36.5 percent of women between the ages of 20-39 are obese. This obesity results in not only metabolic disorders including type II diabetes and cardiovascular disease, but also impaired female fertility.
A. Snider, J. Wood
semanticscholar   +1 more source

Participação do fator de crescimento fibroblástico 18 (FGF18) na maturação nuclear oocitária, expansão das células do cumulus e produção in vitro de embriões bovinos [PDF]

open access: yes, 2015
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biologia Celular e do Desenvolvimento, Florianópolis, 2015.Este trabalho propôs estudar a ação do Fator de Crescimento ...
Silva, Yago Pinto da
core  

CRISPR and Gene Augmentation Rescue Trabecular Meshwork Dysfunction in iPSC Models of Lowe Syndrome

open access: yesAdvanced Science, EarlyView.
By modeling Lowe syndrome using patient‐derived iPSCs, this study establishes a human disease model that faithfully recapitulates OCRL deficiency‐associated ciliary and cytoskeletal defects. The model enables evaluation of both mutation‐agnostic DNA augmentation and CRISPR‐mediated mutation correction strategies, both of which restore OCRL function and
Siyu Chen   +11 more
wiley   +1 more source

Oocyte and embryo quality in

open access: yes, 1999
Egg quality is one of the most important factors determining larval viability. The study of oocytes released by ‘wild' broodstock will contribute to the definition of quality criteria applied to hatcheries as well as being an indicator of the oyster ...
Domitilia Matias   +3 more
core   +1 more source

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