Results 101 to 110 of about 420,620 (395)
SET Improved Oocyte Maturation by PP2A and Inhibited Oocyte Apoptosis in Mouse Oocytes
Abstract Background: SET is a multifunctional protein involved in a variety of molecular processes such as transcription control, chromatin remodeling, cell apoptosis, and cell-cycle regulation. In ovaries SET is predominantly expressed in theca cells and oocytes. And in PCOS patients the expression of SET was increased than normal people.
Lingling Gao+4 more
openaire +2 more sources
RSPO2 and GDF9:BMP15 heterodimers—core components of oocyte‐secreted factors (OSFs)—coordinate to shape the molecular architecture of preantral granulosa cells via gene‐specific synergistic and antagonistic regulation, mediated through CTNNB1–SMAD2 signaling crosstalk.
Yingmei Wang+7 more
wiley +1 more source
Arachidonic Acid as a Possible Negative Feedback Inhibitor of Nicotinic Acetylcholine Receptors on Neurons [PDF]
Neuronal acetylcholine receptors, being highly permeable to calcium, are likely to regulate calcium-dependent events in neurons. Arachidonic acid is a membrane-permeant second messenger that can be released from membrane phospholipids by phospholipases ...
Berg, Darwin K.+3 more
core +2 more sources
Mitochondria provide the primary source of ATP in the oocyte and early embryo and mitochondrial dysfunction and deficit of mitochondria‐derived ATP has been linked to suboptimal developmental competence.
C. Dalton, G. Szabadkai, J. Carroll
semanticscholar +1 more source
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li+17 more
wiley +1 more source
Mammalian oocytes are arrested in the dictyate stage of meiotic prophase I for long periods of time, during which the high concentration of the p53 family member TAp63α sensitizes them to DNA damage-induced apoptosis.
Daniel Coutandin+15 more
doaj +1 more source
Laser microdissection as a new approach to prefertilization genetic diagnosis [PDF]
The genetic status of oocytes can be determined by polar body (PB) analysis. Following PB extraction, a genetic evaluation is performed. As each PB contains the complementary genetic material of the oocyte, PB analysis reveals information about its ...
Buchholz, Tina+2 more
core +1 more source
Development in vitro of mouse oocytes from primordial follicles.
The objective of these studies was to achieve complete oocyte development in vitro beginning with the oocytes in the primordial follicles of newborn mouse ovaries.
J. Eppig, M. O'Brien
semanticscholar +1 more source
Oocyte-secreted factors enhance oocyte developmental competence
The capacity of fully grown oocytes to regulate their own microenvironment by paracrine factors secreted by the oocyte (oocyte-secreted factors, OSFs) may in turn contribute to oocyte developmental competence. Here, we investigated if OSFs have a direct influence on oocyte developmental competence during in vitro maturation (IVM). Bovine cumulus-oocyte
Hussein, T., Thompson, J., Gilchrist, R.
openaire +4 more sources
Different from mitosis, the female meiosis undergoes asymmetric division that produces haploid oocytes and polar body, which is essential for retaining maternal components to support subsequent fertilization and embryo development. However, the underlying mechanisms are still largely unknown.
Yu Li+6 more
wiley +1 more source