Results 41 to 50 of about 49,023 (222)

Spire stimulates nucleation by Cappuccino and binds both ends of actin filaments. [PDF]

open access: yes, 2020
The actin nucleators Spire and Cappuccino synergize to promote actin assembly, but the mechanism of their synergy is controversial. Together these proteins promote the formation of actin meshes, which are conserved structures that regulate the ...
Bailey, Hannah M   +3 more
core  

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

More Than DNA Methylation: Does Pleiotropy Drive the Complex Pattern of Evolution of Dnmt1?

open access: yesFrontiers in Ecology and Evolution, 2020
DNA methylation is an important chromatin modification that can stably alter gene expression in cells and maintain genome integrity in plants and vertebrates.
Ashley U. Amukamara   +6 more
doaj   +1 more source

Resource Availability Modulates Gene Expression Across Life Stages in a Migratory Butterfly. [PDF]

open access: yesMol Ecol
ABSTRACT Natural populations are in constant need of balancing resource allocation to compensate for seasonal environmental variation. In many insects, a well‐established trade‐off between migration and reproduction exists. While this trade‐off has been characterised phenotypically for decades, the underlying regulatory pathways are poorly understood ...
Shipilina D   +8 more
europepmc   +2 more sources

The effect of salinity on transovarial transmission of a microsporidian infecting Gammarus duebeni [PDF]

open access: yes, 1997
This is an investigation of the impact of salinity on transovarial transmission and burden of a microsporidian sex ratio distorter in the inter-tidal crustacean Gammarus duebeni.
Dunn, A.M., Hatcher, M.J.
core   +1 more source

Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization

open access: yesAdvanced Science, EarlyView.
This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin   +11 more
wiley   +1 more source

Peptides in insect oogenesis [PDF]

open access: yesCurrent Opinion in Insect Science, 2019
The physiological control of reproduction in insects depends on a combination of environmental and internal cues. In the adult stage, insects become sexually mature and generate gametes. In females, the latter process is designated as oogenesis. Peptides are a versatile class of extracellular signalling molecules that regulate many processes, including
Lenaerts, C.   +4 more
openaire   +2 more sources

Histological Investigation of the Female Gonads of Chiropsalmus quadrumanus (Cubozoa: Cnidaria) Suggests Iteroparous Reproduction

open access: yesDiversity, 2023
The box jellyfish Chiropsalmus quadrumanus (Chirodropida: Cubozoa: Cnidaria) is common in warm waters. Although it is assumed that external fertilization is a characteristic of Chirodropida, the life history of C.
Jimena García-Rodríguez   +6 more
doaj   +1 more source

The Role of Diaphanous in Ring Canal Development in Drosophila melanogaster [PDF]

open access: yes, 2016
Infertility is a widespread condition that does not always have a known cause, and for which we often do not have a cure. One potential cause of infertility is defects in gametogenesis, or the formation of sperm and egg.
Kindred, Alexandra M.
core   +1 more source

USP9X as a Candidate Mediator of Prenatal Aspirin‐Induced Ovarian Reserve Reduction in Offspring Mice

open access: yesAdvanced Science, EarlyView.
This study suggests that prenatal aspirin exposure is associated with reduced ovarian reserve in offspring, associated with HDAC1‐linked epigenetic downregulation of Usp9x as a candidate mechanism. These preclinical findings provide new insights into fetal‐origin ovarian disorders and contribute to the evidence base concerning aspirin's gestational ...
Yating Li   +11 more
wiley   +1 more source

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