Results 161 to 170 of about 16,336,802 (316)

Efficacy and safety of visepegenatide as an add-on therapy to metformin in patients with type 2 diabetes: a randomised, double-blind, parallel, placebo-controlled, phase 3 studyResearch in context

The Lancet Regional Health. Western Pacific
Summary: Background: Visepegenatide, a once-weekly glucagon-like peptide-1 receptor agonist injection, demonstrated effective glycaemic control and good tolerability without the requirement of dose titration in the two completed phase 2 studies.
Xiaoling Cai, Linong Ji, Mingxia Yuan, Jianhua Ma, Fang Bian, Sheli Li, Wuyan Pang, Shuang Yan, Huimin Zhou, Minghui Hou, Wenhui Li, Ying Jia, Li Liu, Ke Ding, Michael Xu   +14 more
doaj   +1 more source

Intra‐articular Orthobiologics Show Statistically but Not Clinically Meaningful Improvements Compared With Viscosupplementation in Knee Osteoarthritis: A Network Meta‐analysis of Randomized Controlled Trials

Arthroscopy, EarlyView.
Purpose To evaluate the comparative effectiveness of intra‐articular platelet‐rich plasma (PRP), stromal vascular fraction (SVF), bone marrow aspirate concentrate (BMAC), umbilical cord‐derived mesenchymal stem cell (UC‐MSC), and hyaluronic acid (HA) for pain relief and functional improvement in patients with knee osteoarthritis through network meta ...
Joo Hyung Han, Min Jung, Kwangho Chung, Hyun‐Soo Moon, Se‐Han Jung, Sung‐Hwan Kim   +5 more
wiley   +1 more source

Availability and Pricing of Orthobiologic Knee Injections Vary by Practice Type but Not by Community Socioeconomic Vulnerability in Suburban New York

Arthroscopy, Sports Medicine, and Rehabilitation, EarlyView.
Purpose To assess the availability, price transparency, and pricing of platelet‐rich plasma (PRP), bone marrow aspirate concentration, and stem cell injections for knee osteoarthritis (OA) among orthopaedic sports medicine (OSM) practices and alternative clinics in suburban New York and to evaluate the impact of the economic status of a population on ...
Tracy M. Tauro, Benjamin Hershfeld, Katharine Chen, Ran Lampert, Adam D. Bitterman, Randy M. Cohn, Nicholas A. Sgaglione   +6 more
wiley   +1 more source

Long‐term efficacy of adjunctive cenobamate: Open‐label extension of a randomized, placebo‐controlled study in a multinational Asian population [PDF]

Sang Kun Lee, Paul N. Yu, Eunyeong Choe, Louis Ferrari, Kyoung Heo, Seung Bong Hong, Zhen Hong, Koji Iida, Yong Heui Jeon, Jiwon Jung, Marc Kamin, Kensuke Kawai, Ji Hyun Kim, Myung Won Kim, Xiao‐Rong Liu, Jungshin Park, William E. Rosenfeld, Takamichi Yamamoto, Dong Zhou, Suiqiang Zhu, Sunita N. Misra   +20 more
openalex   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

Effects of prefrontal transcranial direct current stimulation on open-label placebo responses [PDF]

Britt Lou Brehm, Anna-Maria Macha, Phillip Alexander Denk, Anne Weigand, Michael Schaefer   +4 more
openalex   +1 more source

Biologic and Targeted Synthetic Disease‐Modifying Antirheumatic Drugs Do Not Arrest Bone Loss in Patients With Rheumatoid Arthritis: A Long‐Term Multicenter Observational Study

Arthritis &Rheumatology, EarlyView.
Objective Osteoporosis causes fractures that further increase the disease burden of rheumatoid arthritis (RA); however, osteoporosis treatment rates remain low. Although several studies have reported that biologic or targeted synthetic disease‐modifying antirheumatic drugs (b/tsDMARDs) can prevent or improve osteoporosis in RA, our large‐scale, real ...
Takafumi Aritomi, Koshiro Sonomoto, Shingo Nakayamada, Hiroaki Tanaka, Atsushi Nagayasu, Satoshi Kubo, Ippei Miyagawa, Ayako Yamaguchi, Naoaki Ohkubo, Yasuyuki Todoroki, Yurie Satoh‐Kanda, Masanobu Ueno, Ryuichiro Kanda, Yuya Fujita, Masashi Funada, Hidenori Sakai, Satsuki Matsunaga, Hiroaki Tanaka, Masayuki Shinojima, Hiroki Kawamura, Kazuki Takahashi, Miyabi Ando, Kazuki Haru, Yusuke Miyazaki, Kentaro Hanami, Masao Nawata, Shunsuke Fukuyo, Keisuke Nakatsuka, Mikiko Tokunaga, Kazuyoshi Saito, Yoshiya Tanaka   +30 more
wiley   +1 more source

Enacting the mind/body connection: the role of self-induced placebo mechanisms

Humanities & Social Sciences Communications
Placebo effects are beneficial mind-body outcomes derived from beliefs or expectations, not explainable as the consequence of active medical treatments. These phenomena have long been considered a result of external manipulation, generally obtained with ...
Francesco Pagnini, Diletta Barbiani, Francesca Grosso, Cesare Cavalera, Eleonora Volpato, Giacomo Andrea Minazzi, Valentina Poletti, Giuseppe Riva, Deborah Phillips   +8 more
doaj   +1 more source

Cortical and trabecular bone changes associated with tibolone in postmenopausal women: A randomized, open-label study compared with estrogen therapy and placebo [PDF]

Griselda-Adriana Cruz-Priego, Miguel Ángel Guagnelli, Sergio Ortiz Santiago, Lizett Castrejón-Delgado, Ludovic Humbert, Martha A. Sánchez-Rodrı́guez, Patricia Clark   +6 more
openalex   +1 more source

What are the effects of an Open-Label Placebo on pain?

Placebo treatments can have a substantial influence on subjective symptoms. Open-label placebos are a method of harnessing the placebo effect ethically, respecting both patient autonomy and informed consent.
Bartholomew, Emerson (Mohamed Jaim Emerson)
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