Roles of administration route, expectation, and belief in placebos in a randomized controlled trial with open-label placebos [PDF]
Scientific ReportsRecent reports challenge the view that placebos need to be given in deception. Numerous studies report remarkable effects when giving placebos honestly in an open way. However, the mechanisms of open-label placebos still remain to be cleared. For example,
Michael Schaefer +2 more
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Correction: Providing open-label placebos remotely-A randomized controlled trial in allergic rhinitis. [PDF]
PLoS ONE, 2021 [This corrects the article DOI: 10.1371/journal.pone.0248367.].
Tobias Kube +3 more
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A qualitative study of imaginary pills and open-label placebos in test anxiety [PDF]
PLoS ONE, 2023 Background The efficacy of open-label placebos (OLPs) has been increasingly demonstrated and their use holds promise for applications compatible with basic ethical principles.
Sarah Buergler +9 more
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Open-label placebos enhance test performance and reduce anxiety in learner drivers: a randomized controlled trial [PDF]
Scientific ReportsPassing the driving school test can be very challenging, especially in big cities, where up to 52% of all students fail this test. Consequently, many learner drivers experience stress and anxiety.
Michael Schaefer, Sören Enge
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Open-label placebos—a systematic review and meta-analysis of experimental studies with non-clinical samples [PDF]
Scientific Reports, 2023 The use of open-label placebos (OLPs) has shown to be effective in clinical trials. We conducted a systematic review and meta-analysis to examine whether OLPs are effective in experimental studies with non-clinical populations. We searched five databases
Lukas Spille +4 more
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Open-label placebos for menopausal hot flushes: a randomized controlled trial. [PDF]
Sci Rep, 2020 AbstractThis study investigated the efficacy of an open-label placebo (OLP) treatment for menopausal hot flushes. Women with at least five moderate or severe hot flushes per day were allocated to receive four weeks of OLP for twice a day or no-treatment. Intention-to-treat analyses included n = 100 women.
Pan Y +5 more
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Effects of Open-Label Placebos on Visual Food Cue Reactivity in Children and Adolescents [PDF]
ChildrenBackground: A high level of food cue reactivity (FCR) is a risk factor for overeating and weight gain. This randomized trial investigated whether open-label placebos (OLPs: placebos honestly administered) can reduce FCR (reported appetite) in children ...
Anne Schienle +4 more
doaj +2 more sources
Acceptance of Open-Label Placebos Is Linked to Holistic Health Beliefs and Thinking Styles [PDF]
Behavioral SciencesOpen-label placebos (OLPs) have demonstrated benefits across multiple conditions; however, the factors influencing their acceptance or rejection remain unclear.
Arved Seibel +2 more
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Effects of open-label placebos and self-monitoring in skin-picking disorder: a randomized crossover trial [PDF]
Frontiers in PsychiatryBackgroundSymptom reduction in skin-picking disorder (SPD) has previously been demonstrated using deceptive placebo treatments. However, to date, no study has investigated the effects of open-label placebos (OLPs) in this context.MethodFifty-two ...
Anne Schienle +2 more
doaj +2 more sources
Open-label Placebos for Wound Healing: A Randomized Controlled Trial [PDF]
Annals of Behavioral Medicine, 2018 Open-label placebos are a novel treatment option, in which participants take placebos with full knowledge that they do not contain active medicine. Open-label placebo treatments have been shown to result in patient-reported symptom improvements, but they have not been tested on objectively measurable physiological outcomes such as wound healing.The ...
Paul Jarrett +2 more
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