Effects of open-label placebos on test performance and psychological well-being in healthy medical students: a randomized controlled trial [PDF]
Scientific Reports, 2021 Psychological distress is prevalent in students and can predispose to psychiatric disorders. Recent findings indicate that distress might be linked to impaired cognitive performance in students.
Julian Kleine-Borgmann
exaly +4 more sources
Roles of administration route, expectation, and belief in placebos in a randomized controlled trial with open-label placebos [PDF]
Scientific ReportsRecent reports challenge the view that placebos need to be given in deception. Numerous studies report remarkable effects when giving placebos honestly in an open way. However, the mechanisms of open-label placebos still remain to be cleared. For example,
Michael Schaefer +2 more
doaj +4 more sources
Open-label placebos—a systematic review and meta-analysis of experimental studies with non-clinical samples [PDF]
Scientific Reports, 2023 The use of open-label placebos (OLPs) has shown to be effective in clinical trials. We conducted a systematic review and meta-analysis to examine whether OLPs are effective in experimental studies with non-clinical populations. We searched five databases
Lukas Spille +4 more
doaj +3 more sources
Open-label placebos enhance test performance and reduce anxiety in learner drivers: a randomized controlled trial [PDF]
Scientific ReportsPassing the driving school test can be very challenging, especially in big cities, where up to 52% of all students fail this test. Consequently, many learner drivers experience stress and anxiety.
Michael Schaefer, Sören Enge
doaj +3 more sources
Can open label placebos improve pain and gluten tolerance via open label placebos in fibromyalgia patients? A study protocol for a randomised clinical trial in an outpatient centre [PDF]
BMJ Open, 2023 Introduction Fibromyalgia syndrome (FMS) is defined as a medical condition with chronic widespread musculoskeletal pain accompanied by mood disorders, fatigue and sleep disturbances. Treatment of this condition can often be challenging.
Margitta Worm +3 more
doaj +4 more sources
Open label placebo: can honestly prescribed placebos evoke meaningful therapeutic benefits?
BMJ, 2018 Results from small clinical trials suggesting that placebos can be ethically and effectively used in clinical practice warrant further study, argue Ted Kaptchuk and Franklin ...
Ted J. Kaptchuk, Franklin G. Miller
semanticscholar +6 more sources
Effects of a probiotic treatment (Enterococcus faecalis) and open-label placebo on symptoms of allergic rhinitis: study protocol for a randomised controlled trial [PDF]
BMJ Open, 2019 Introduction Several studies suggest that gut microbiota may play an important role in allergic diseases. The present trial aims to examine effects of the probiotic Enterococcus faecalis on symptoms of allergic rhinitis in patients.
Paul Enck, Michael Schaefer
doaj +3 more sources
A qualitative study of imaginary pills and open-label placebos in test anxiety [PDF]
PLoS ONE, 2023 Background The efficacy of open-label placebos (OLPs) has been increasingly demonstrated and their use holds promise for applications compatible with basic ethical principles.
Sarah Buergler +9 more
doaj +4 more sources
Open-label placebos reduce test anxiety and improve self-management skills: A randomized-controlled trial [PDF]
Scientific Reports, 2019 Test anxiety is a condition in which people experience extreme distress and anxiety before and in test situations. It affects up to 40 percent of all students.
Michael Schaefer, Claudia Denke
exaly +3 more sources
Open-label dose-extending placebos for opioid use disorder: a protocol for a randomised controlled clinical trial with methadone treatment [PDF]
BMJ Open, 2019 Introduction More than 2 million individuals in the USA have an opioid use disorder (OUD). Methadone maintenance treatment is the gold standard of medication-based treatment for OUD, but high-dose methadone is associated with cardiotoxicity and ...
Annabelle M Belcher +15 more
doaj +3 more sources