Providing open-label placebos remotely-A randomized controlled trial in allergic rhinitis. [PDF]
PLoS ONE, 2021 BackgroundPlacebos can reduce physical symptoms even when provided with full honesty and disclosure. Yet, the precise mechanisms underlying the effects of "open-label placebos" (OLPs) have remained subject of debate.
Tobias Kube +3 more
doaj +6 more sources
Open-label placebos for menopausal hot flushes: a randomized controlled trial. [PDF]
Sci Rep, 2020 AbstractThis study investigated the efficacy of an open-label placebo (OLP) treatment for menopausal hot flushes. Women with at least five moderate or severe hot flushes per day were allocated to receive four weeks of OLP for twice a day or no-treatment. Intention-to-treat analyses included n = 100 women.
Pan Y +5 more
europepmc +6 more sources
Are open‐Label Placebos Ethical? Informed Consent and Ethical Equivocations [PDF]
Bioethics, 2016 AbstractThe doctor‐patient relationship is built on an implicit covenant of trust, yet it was not until the post‐World War Two era that respect for patient autonomy emerged as an article of mainstream medical ethics. Unlike their medical forebears, physicians today are expected to furnish patients with adequate information about diagnoses, prognoses ...
Charlotte R Blease, Luana Colloca
exaly +6 more sources
Effects of open-label placebos on test performance and psychological well-being in healthy medical students: a randomized controlled trial [PDF]
Scientific Reports, 2021 Psychological distress is prevalent in students and can predispose to psychiatric disorders. Recent findings indicate that distress might be linked to impaired cognitive performance in students.
Julian Kleine-Borgmann
exaly +4 more sources
Open-label placebos—a systematic review and meta-analysis of experimental studies with non-clinical samples [PDF]
Scientific Reports, 2023 The use of open-label placebos (OLPs) has shown to be effective in clinical trials. We conducted a systematic review and meta-analysis to examine whether OLPs are effective in experimental studies with non-clinical populations. We searched five databases
Lukas Spille +4 more
doaj +3 more sources
Open-label placebos enhance test performance and reduce anxiety in learner drivers: a randomized controlled trial [PDF]
Scientific ReportsPassing the driving school test can be very challenging, especially in big cities, where up to 52% of all students fail this test. Consequently, many learner drivers experience stress and anxiety.
Michael Schaefer, Sören Enge
doaj +3 more sources
Lay perspectives of the open-label placebo rationale: a qualitative study of participants in an experimental trial [PDF]
BMJ Open, 2021 Objectives To analyse participants’ concepts about the open-label placebo (OLP) effect; to explore their views about the discussion points that are applied in conventional OLP trials and to examine their experiences of taking part in an OLP trial.Design ...
Cosima Locher +5 more
doaj +3 more sources
Open-label placebos reduce test anxiety and improve self-management skills: A randomized-controlled trial [PDF]
Scientific Reports, 2019 Test anxiety is a condition in which people experience extreme distress and anxiety before and in test situations. It affects up to 40 percent of all students.
Michael Schaefer, Claudia Denke
exaly +3 more sources
Correction: Providing open-label placebos remotely-A randomized controlled trial in allergic rhinitis. [PDF]
PLoS ONE, 2021 [This corrects the article DOI: 10.1371/journal.pone.0248367.].
Tobias Kube +3 more
doaj +2 more sources
Scientific Reports, 2023 Placebo effects are known for numerous clinical symptoms. Until recently, deception of placebos was thought to be essential for placebo effects, but intriguing new studies suggest that even placebos without concealment (open-label placebos) may help ...
Michael Schaefer +2 more
doaj +2 more sources