Results 191 to 200 of about 3,973 (220)

The Placebo Effect in Rare Disease Clinical Trials: Measurement, Impact, and Statistical Approaches for Patient-as-Own-Control Designs. [PDF]

Clin Transl Sci
Summar ML, Woodcock J.
europepmc   +1 more source

Use of DNA profiling to resolve HIV status in a person using injectable cabotegravir for HIV pre-exposure prophylaxis. [PDF]

J Clin Pathol
Fogel JM, Salih MA, Haddaway K, Marzinke MA, Marshall C, Wang Z, Cummings V, Piwowar-Manning E, Rooney JF, McCauley M, Grinsztejn B, Landovitz RJ, Eshleman SH.   +12 more
europepmc   +1 more source

Justice for Placebo: Placebo Effect in Clinical Trials and Everyday Practice. [PDF]

Medicines (Basel)
Knezevic NN, Sic A, Worobey S, Knezevic E.   +3 more
europepmc   +1 more source

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Deceptive but not open label placebos attenuate motion-induced nausea

Journal of Psychosomatic Research, 2019
Nausea is a common complaint, known to respond to the placebo effect. Existing research has employed deception when administering placebos for nausea, limiting therapeutic translation on ethical grounds. We therefore examined the potential of non-deceptive open-label placebos (OLPs) to reduce nausea.Galvanic Vestibular Stimulation (GVS) and Virtual ...
Ben Colagiuri
exaly   +3 more sources

Worth a try – A survey on the general acceptance of open-label placebos

Journal of Psychosomatic Research, 2023
Ulrike Bingel
exaly   +4 more sources

Choice over placebo administration enhances open-label placebo hypoalgesia

Pain, 2023
Abstract Many studies indicate that deceptively administered placebos can improve pain outcomes. However, the deception involved presents an ethical barrier to translation because it violates informed consent and patient autonomy. Open-label placebos (OLPs), inert treatments that are openly administered as placebos, have been proposed as an ...
Biya Tang, Evan Livesey, Ben Colagiuri
openaire   +2 more sources

Open-Label Placebo Treatment for Experimental Pain: A Randomized-Controlled Trial with Placebo Acupuncture and Placebo Pills

Journal of Integrative and Complementary Medicine, 2022
Objective: An open-label placebo (OLP) is a placebo treatment in which the patient is aware that the treatment is a placebo. OLPs are considered effective for reducing pain, and previous studies have shown a stronger placebo effect for placebo acupuncture than for placebo pills.
Seoyoung Lee, Dha-Hyun Choi, Minyoung Hong, In-Seon Lee, Younbyoung Chae   +4 more
openaire   +2 more sources

Open-Label Placebo: Reflections on a Research Agenda

Perspectives in Biology and Medicine, 2018
Open-label placebos (OLP)-placebo pills honestly prescribed-have challenged the notion that placebos require either deception or concealment to evoke salubrious benefits. This essay describes how the author arrived at the counter-intuitive OLP hypothesis, discusses evidence for OLP effectiveness, and examines mechanistic explanations for OLP.
openaire   +2 more sources

Open-label nondeceptive placebos

Open-label placebos (OLPs), where patients are informed they are receiving a placebo, challenge the traditional notion that placebos require deception to be effective. Recent research has shown that OLPs can positively impact subjective outcomes, such as pain perception and symptom severity, across various conditions like chronic pain, mental disorders,
Julian, Kleine-Borgmann, Ulrike, Bingel
openaire   +2 more sources