Placebo Effects in Modern Medicine: Mechanisms, Clinical Evidence, Limitations, and Future Directions. [PDF]
Alnasralla MB, Nasralla BH.
europepmc +1 more source
Understanding and leveraging placebo and nocebo effects in perioperative care: a cross-sectional survey of German-speaking anesthesiologists. [PDF]
Wessels J +7 more
europepmc +1 more source
First-in-Human Study of a Long-Acting GLP-1 Receptor Agonist (TE-8105) in Overweight or Obese Adults Without Type 2 Diabetes Mellitus. [PDF]
Chuang YS +7 more
europepmc +1 more source
Placebo and nocebo effects on pain through the lens of the predictive brain: Neurobiological mechanisms and translational implications. [PDF]
Zamfira DA +4 more
europepmc +1 more source
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Deceptive but not open label placebos attenuate motion-induced nausea
Journal of Psychosomatic Research, 2019Nausea is a common complaint, known to respond to the placebo effect. Existing research has employed deception when administering placebos for nausea, limiting therapeutic translation on ethical grounds. We therefore examined the potential of non-deceptive open-label placebos (OLPs) to reduce nausea.Galvanic Vestibular Stimulation (GVS) and Virtual ...
Ben Colagiuri
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Worth a try – A survey on the general acceptance of open-label placebos
Journal of Psychosomatic Research, 2023Katarina Forkmann, Ulrike Bingel
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Choice over placebo administration enhances open-label placebo hypoalgesia
Pain, 2023Abstract Many studies indicate that deceptively administered placebos can improve pain outcomes. However, the deception involved presents an ethical barrier to translation because it violates informed consent and patient autonomy. Open-label placebos (OLPs), inert treatments that are openly administered as placebos, have been proposed as an ...
Biya Tang, Evan Livesey, Ben Colagiuri
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Objective: An open-label placebo (OLP) is a placebo treatment in which the patient is aware that the treatment is a placebo. OLPs are considered effective for reducing pain, and previous studies have shown a stronger placebo effect for placebo acupuncture than for placebo pills.
Seoyoung Lee +4 more
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Open-Label Placebo: Reflections on a Research Agenda
Perspectives in Biology and Medicine, 2018Open-label placebos (OLP)-placebo pills honestly prescribed-have challenged the notion that placebos require either deception or concealment to evoke salubrious benefits. This essay describes how the author arrived at the counter-intuitive OLP hypothesis, discusses evidence for OLP effectiveness, and examines mechanistic explanations for OLP.
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