Results 201 to 210 of about 3,973 (220)
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Open‐label use of placebos in the treatment of ADHD: a pilot study
Child: Care, Health and Development, 2007AbstractBackground This study examined short‐term efficacy, side effects and acceptability of a placebo treatment procedure designed to maintain children with attention deficit hyperactivity disorder (ADHD) on 50% of their usual stimulant dose.Methods An open‐label prospective crossover trial was conducted in 26 children with ADHD, ages 7–15 years ...
A D, Sandler, J W, Bodfish
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More than consent for ethical open-label placebo research
Journal of Medical Ethics, 2020Recent studies have explored the effectiveness of open-label placebos (OLPs) for a variety of conditions, including chronic pain, cancer-related fatigue and irritable bowel syndrome. OLPs are thought to sidestep traditional ethical worries about placebos because they do not involve deception: with an OLP, patients or subjects are told outright that ...
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Open-label nondeceptive placebo analgesia is blocked by the opioid antagonist naloxone
Pain, 2022Abstract Open-label placebos, or placebos without deception, have been found to induce analgesia, a challenging concept that need to be investigated in detail. In particular, what we need to know is the mechanism through which analgesia is induced when no deception is involved. In this study, we show for the first time that open-label placebo
Fabrizio Benedetti +3 more
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A Fictionalist Account of Open-Label Placebo
The Journal of Medicine and Philosophy: A Forum for Bioethics and Philosophy of MedicineAbstract The placebo effect is now generally defined widely as an individual’s response to the psychosocial context of a clinical treatment, as distinct from the treatment’s characteristic physiological effects. Some researchers, however, argue that such a wide definition leads to confusion and misleading implications.
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European Journal of Applied Physiology, 2019
Recent evidence suggests that deception may not be necessary for placebos to improve clinical outcomes. We tested the hypothesis that placebo and open-label placebo (OLP) treatments would acutely improve strength and voluntary activation, as well as minimize neuromuscular fatigue, in untrained participants.Twenty-one males (n = 11) and females (n = 10)
Alina P. Swafford +5 more
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Recent evidence suggests that deception may not be necessary for placebos to improve clinical outcomes. We tested the hypothesis that placebo and open-label placebo (OLP) treatments would acutely improve strength and voluntary activation, as well as minimize neuromuscular fatigue, in untrained participants.Twenty-one males (n = 11) and females (n = 10)
Alina P. Swafford +5 more
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Children's and parents' perspectives on open‐label use of placebos in the treatment of ADHD
Child: Care, Health and Development, 2007AbstractBackground The purpose of this study was to examine the efficacy and acceptability of an open‐label conditioned placebo dose reduction (CPDR) treatment in 70 children with attention deficit hyperactivity disorder (ADHD). This paper focuses on the qualitative data from the study.Methods Following a double‐blind, crossover dose finding ...
A, Sandler, C, Glesne, G, Geller
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Time to reflect on open-label placebos and their value for clinical practice
Pain, 2023Caitlin M.P. Jones +5 more
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Enthusiastic claims for open-label placebo pills ignore the evidence
Pain, 2020Anita B, Amorim +2 more
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From Placebo to 'Open-Label Placebo' to Open Altogether
2014Mommaerts, Jean-Luc, Devroey, Dirk
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Open-Label Placebo in Children With Abdominal Pain or IBS
AAP Grand Rounds, 2022openaire +1 more source