Results 21 to 30 of about 151,642 (322)

Can observational learning reinforce open-label placebo hypoalgesia? [PDF]

open access: hybridPain, 2023
Previous research has indicated that an open-label placebo can reduce pain in both healthy participants and chronic pain patients. As nondeceptive placebos seem to be an effective and more ethical alternative to deceptive placebos, optimizing this kind of treatment is essential.
Brączyk J, Bąbel P.
europepmc   +5 more sources

Placebo Effects of Open-label Verbal Suggestions on Itch [PDF]

open access: goldActa Dermato Venereologica, 2018
Placebo effects are positive outcomes that are not due to active treatment components, which may be elicited even when patients are aware of receiving an inert substance (open-label). This proof-of-principle study investigated for the first time whether open-label placebo effects on itch can be induced by verbal suggestions alone.
Stefanie H. Meeuwis   +6 more
openalex   +8 more sources

A randomized controlled trial of effects of open-label placebo compared to double-blind placebo and treatment-as-usual on symptoms of allergic rhinitis

open access: yesScientific Reports, 2023
Placebo effects are known for numerous clinical symptoms. Until recently, deception of placebos was thought to be essential for placebo effects, but intriguing new studies suggest that even placebos without concealment (open-label placebos) may help ...
Michael Schaefer   +2 more
doaj   +2 more sources

The Ethics of Open-Label Placebos in Pediatrics [PDF]

open access: yesPediatrics, 2017
* Abbreviation: ADHD — : attention-deficit/hyperactivity disorder Physicians have long debated the ethics of prescribing placebos as medical therapeutics. Placebos (sham treatments such as sugar pills or saline injections) are thought to elicit improvements in clinical outcomes by mimicking medical therapies, thereby improving patients ...
Brit Trogen, A. Caplan, P. Klass
semanticscholar   +4 more sources

Placebos in the era of open‐label trials: An update for clinicians [PDF]

open access: yesEuropean Journal of Clinical Investigation, 2018
Placebos have been used extensively by vast numbers of physicians, in a majority of clinical trials. Placebo effects involve behavioural, psychological and genetic factors and have been subject to ethical controversies stemming from the use of deception ...
I. Sagy   +3 more
semanticscholar   +4 more sources

Open-label Placebos for Wound Healing: A Randomized Controlled Trial. [PDF]

open access: yesAnnals of Behavioral Medicine, 2018
Open-label placebos are a novel treatment option, in which participants take placebos with full knowledge that they do not contain active medicine. Open-label placebo treatments have been shown to result in patient-reported symptom improvements, but they have not been tested on objectively measurable physiological outcomes such as wound healing.The ...
Ashwini Mathur   +3 more
semanticscholar   +4 more sources

Open-Label Placebo Treatment for Acute Postoperative Pain (OLP-POP Study): Study Protocol of a Randomized Controlled Trial

open access: yesFrontiers in Medicine, 2021
Introduction: Open-label placebos have been proposed as way of using long recognized analgesic placebo effects in an ethical manner. Recent evidence shows efficacy of open-label placebos for clinical conditions, but there is need for more research on ...
Dilan Sezer   +10 more
doaj   +2 more sources

"Let's see what happens:"-Women's experiences of open-label placebo treatment for menopausal hot flushes in a randomized controlled trial.

open access: yesPLoS ONE, 2022
Open-label (honestly prescribed) placebos are an ethical way to evoke placebo effects in patients. As part of a mixed-methods study, we conducted in-depth interviews with eight menopausal women who underwent and benefitted from open-label placebo ...
Yiqi Pan   +3 more
doaj   +2 more sources

Open-label placebos enhance test performance and reduce anxiety in learner drivers: a randomized controlled trial [PDF]

open access: yesScientific Reports
Passing the driving school test can be very challenging, especially in big cities, where up to 52% of all students fail this test. Consequently, many learner drivers experience stress and anxiety.
Michael Schaefer, Sören Enge
doaj   +2 more sources

Effects of placebos without deception compared with no treatment: A systematic review and meta‐analysis [PDF]

open access: yesJournal of Evidence-Based Medicine, 2017
Aim Our aim was to address the clinical efficacy of open-label placebos compared with no treatment by systematic review, and meta-analysis where possible.
James E G Charlesworth   +2 more
exaly   +3 more sources

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